Were they taking the large doses of vitamin B6 supplement to help with relief of PMS, Carpal Tunnel Syndrome, asthma, or heart disease which research has showed vitamin B6 does not have any significant effect on the named above. Vitamin B6
toxicity causes temporary neurological
symptoms, which, according to the literature, usually take up to 6 months for it to resolve itself for majority of people. There are some people who do have permanent damage.