Phenytoin in pregnancy

Common Questions and Answers about Phenytoin in pregnancy

dilantin

Avatar m tn In a small study, phenytoin-induced seizures occurred most often in patients with serum phenytoin concentrations of 50 mcg/ml or higher.[393] Peripheral neuropathy, usually occurring weeks to months after drug initiation, has also been reported in patients receiving phenytoin. A single case report describes the onset of neuropathy within a few hours of drug administration.[9780] Adverse GI effects of phenytoin therapy include nausea/vomiting, constipation, abdominal pain, and anorexia.
Avatar f tn Folic acid supplementation in folate-deficient patients with epilepsy changes the pharmacokinetics of phenytoin, usually leading to lower serum phenytoin concentrations and possible seizure breakthrough..." It however says that initiation of Folic acid and phenytoin together is beneficial. Since you can't go back and start all over again, you can take a small dose. It has been observed that as los as 1mg dose can perturb phenytoin’s levels, You may take doses lower than 1mg/day.
Avatar n tn Combining fluoxetine or paroxetine with phenytoin can also lead to increased phenytoin side effects and reduce blood levels of paroxetine. You really need to discuss the potential drug interactions with your own doctor.
1291453 tn?1272143404 Please note this: "If the level of phenytoin in your blood gets too high, it can cause symptoms such as confusion, rapid involuntary eye movements, blurred vision, slurred speech or clumsy movements. You should tell your doctor if you experience any of these symptoms while taking phenytoin, so that your blood level of phenytoin can be measured and your dose reduced if necessary. " Also, he has had a major surgery, and will need time to recover.
Avatar n tn Ingestion times of phenytoin and antacid preparations containing calcium should be staggered in patients with low serum phenytoin levels to prevent absorption problems”. Taken from http://www.rxlist.com/cgi/generic/phenyt_od.htm Our population is divided into 4 type of metabolizers ranging from rapid to slow metabolizers depending upon the speed of elimination of drug from body. Hence, every person react differently to same drug.
Avatar n tn I don’t have a full description of your consciousness during the lack of speech episodes to decide whether this start is a partial epilepsy which can continue in a generalized or it is a generalized one from the first moment.. in both cases the treatment in Phenytoin and no known to me (till now a treatment to over count its side effects from gingival hypertrophy to the respiratory problems).
Avatar m tn An occasional one or two drink may be fine but moderate or large amount can cause significant increases in blood levels of phenytoin due to induction of hepatic enzymes. Whereas if you are a chronic alcoholic, the phenytoin levels may be lower than expected and can cause seizures. I suggest you consult with your neurologist in this regard. Hope this information helps. Take care.
Avatar f tn Taking Dilantin in early pregnancy may lead to birth defects but they are relatively uncommon. The various defects which may occur are growth delay, limb abnormalities, facial defects; mental retardation etc. Inform your gynecologist about your delayed periods. Take up urine pregnancy test. If you are pregnant your doctor may gradually decrease the dose and stop it and may prescribe an alternative anti seizure medicine which is safe during pregnancy.
Avatar f tn During those times I had not yet been diagnosed and was able to go back to life like normal, however after the diagnosis and being on phenytoin and switching to oxcarbazepine i am feeling awful. Dizzy, nauseated, moody, extremely tired, severe headaches that come and go. All i get from my Neurologist is these are side effects that will eventually go away. Because i never know when these symptoms will come on too strong I have missed a lot of days at work during my probation period.
Avatar f tn My dad who is 81 years old in India is on Citilin 500mg daily. The neurologist prescribed it after he had TIA number of times. He used to get seizures like symptoms and loose his consciousness. He was bedridden and stopped walking completely. Now, he is up on his feet and doing his regular work after regular physiotherapy. At first, he had trigeminal neuralgia and he was on carbamezapine 150mg twice daily and then 300mg twice daily. I just need to know how long he has to be on Citilin.
Avatar f tn we have tried sleep medications in low dosages back in january. he only sleeps 2 - 3 hours per night, and right now im concerned more about his crying before falling asleep. i am at a loss as to what i can do to help him. its like he is crying in pain but went for physical last week and his pediatrician said after the exam it night be his medication or perhaps something happened to his brain during his last seizure. i was tempted to bring him to the er several times.
Avatar f tn A few weeks ago I woke up with yellow crust on the corner of my lips and it went away in 2 days, and today I woke up and it's in the exact same spot again except a little more then before. It doesn't hurt or itch, it feels like my lips are very very dry. I don't smoke, I have grandmal seizures and my medication is phenytoin and kepra but I didn't read anywhere that would be a side effect so I'm worried this could be a STD or something.
Avatar n tn s say the half life of Drug A is 5 hours and you have taken 10mg dose. In the next 5 hours, only 5mg of the drug will remain in the body. In another 5 hours only 2.5mg will remain and then 1.25mg and so on. It takes about 4 -5 half lives for the drug to be completely metabolized. Hence in the case of Depakote, since the half life is 16 ± 3 hours (lets take a maximum of 19 hours), the time for complete metabolism will be 19 X 5 = 95 hours. That means 4 complete days.
5268376 tn?1406179712 Rhythm issues were reported less than 1% of the time in pre-marketing trials, and also in post-marketing reports. Post marketing reports are apparently voluntary and often include things clearly not related to the drug. I have placed the following link to an FDA advisory on Heart Rhythm issues and Zithromax.
Avatar f tn Facial twitches are caused by stress and anxiety, muscle fatigue, side effects of medicines, high intake of caffeine, Parkinson’s disease in elderly, magnesium deficiency etc. Hemi facial spasm may be seen in tumors, multiple sclerosis, stroke etc. treatment may include balanced diet with mineral supplements like potassium, calcium, magnesium, massages for fatigue, B complex supplementation like avocadoes, bananas, legumes etc. drugs like gabapentin, phenytoin are used for hemifacial spasm.
1936411 tn?1333831849 ve heard of that might help with the itch are trying the over the counter antihistamines or antihistamine hydroxyzine (Atarax), anticonvulsants (e.g. gabapentin, carbamazepine, phenytoin), antidepressants (e.g. amitriptyline, paroxetine, mirtazapine), and even Pregabelin (Lyrica)....
Avatar f tn but that was too high I was like a walking zombi, loosing my memory, nerves in hands and legs started to jump, slight quiver in hands, etc. It was awful. I was then lowered to 200mg which I could handle quite well. My levels were checked in Feb.08 and the levels were low at 29, my Dr. raised the dose to 250mg wich moved my levels to 55. which she said was good. In a short time of being on that I started to get the same side affects as on the 300mg. My Dr.
Avatar n tn Dilantin sodium blocks voltage sensitive sodium channels in neurons which leads to a delay in neuronal electrical recovery from inactivation. It is related to barbiturates in chemical structure.It prevents the electrical spread of a focus of irritable tissue from entering normal tissue. Its toxicity depends on the route of administration, duration, exposure and dosage. The route of administration is the most important determinant of toxicity. I hope this helps.
Avatar n tn consult a neurologist immediately, a balanced diet, foods high in potassium, calcium and magnesium, massages to relieve physical stress and fatigue, vitamin B complex rich foods,certain drugs like gabapentin, phenytoin,carbamazepine, botulinum toxin injections. Take care.
Avatar f tn Thus I was speculating as to whether or not Depakote could be a factor, especially since I had pancreatitis in 2003 in the past at which time I was also taking Depakote( 2400mg daily!) Reason also undetermined. I do have osteopenia and must be careful not to fall...and break bones. Thank you for response.
Avatar n tn Issues with Seizure Medications For some people using certain medications, generics can be a problem. This is most often a problem with medications in which even a miniscule change in dose can be ineffective or cause side effects. Dilantin (phenytoin) is one of those medications.
Avatar m tn I am a 23 year old Female who has always been very healthy no colds never had a head ache ect... one year ago in February I had a series of infections then started to gain weight despite being very physically active and on a very strict diet.
Avatar n tn Acute alcohol consumption increases the availability of phenytoin (Dilantin) and the risk of drug-related side effects. Chronic drinking may decrease phenytoin availability, significantly reducing the patient's protection against epileptic seizures, even during a period of abstinence. Any form of alcohol, even beer is contraindicated for some time when you are weaned off dilantin. Sexual activity is an exertional activity which can cause exertional or sexual headache.
Avatar f tn Yet if I need to take an antibiotic I must avoid the mycin class. Mycins effect the metabolism of Phenytoin in the liver, slowing the elimination of it significantly. If I take a mycin class antibiotic, I may overdose on the amount of Phenytoin that I have been taking daily for years, simply based on this interaction. The Supplements you take may have similar effects on other supplements or medications. Be well.
Avatar m tn Trenbolone is a steroid and apart from its action on steroid, it can raise your blood glucose levels, cause rise in BP and affect your pituitary-gonadal axis. Similarly you should not take thyroid hormone supplements unless you are suffering from hypothyroidism. If you want to lose weight or build up muscle mass then do it scientifically through diet and exercise. Please consult your doctor regarding this. Take care!
Avatar n tn I have been on Coumadin for 18 years due to Lupus Anticoagulant (Antiphospholipid Syndrome) and several DVTs. In 2005 had MI with occlusion of the LAD artery and had drug stent inserted and I am still on plavix. My doc has debated when to take me off the Plavix safely....what are the recent studies about this dilemma? thanks so much!