Phenytoin folate

Common Questions and Answers about Phenytoin folate

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Avatar f tn Hello. You have correctly interpreted your research on the topic. And this article does say the same. http://www.ncbi.nlm.nih.gov/pubmed/8520091 It says, "...Serum folate decreases when phenytoin therapy is initiated alone with no folate supplementation. Folic acid supplementation in folate-deficient patients with epilepsy changes the pharmacokinetics of phenytoin, usually leading to lower serum phenytoin concentrations and possible seizure breakthrough...
Avatar m tn How long for serum folate levels to normalize with oral therapy of folic acid?
Avatar m tn In a small study, phenytoin-induced seizures occurred most often in patients with serum phenytoin concentrations of 50 mcg/ml or higher.[393] Peripheral neuropathy, usually occurring weeks to months after drug initiation, has also been reported in patients receiving phenytoin. A single case report describes the onset of neuropathy within a few hours of drug administration.[9780] Adverse GI effects of phenytoin therapy include nausea/vomiting, constipation, abdominal pain, and anorexia.
Avatar n tn Combining fluoxetine or paroxetine with phenytoin can also lead to increased phenytoin side effects and reduce blood levels of paroxetine. You really need to discuss the potential drug interactions with your own doctor.
1291453 tn?1272143404 You should tell your doctor if you experience any of these symptoms while taking phenytoin, so that your blood level of phenytoin can be measured and your dose reduced if necessary. " Also, he has had a major surgery, and will need time to recover. However, any changes need to be reported to the doctor.
Avatar n tn Moban® brand of molindone hydrochloride contains calcium ions which interfere with the absorption of phenytoin. Ingestion times of phenytoin and antacid preparations containing calcium should be staggered in patients with low serum phenytoin levels to prevent absorption problems”. Taken from http://www.rxlist.com/cgi/generic/phenyt_od.htm Our population is divided into 4 type of metabolizers ranging from rapid to slow metabolizers depending upon the speed of elimination of drug from body.
Avatar n tn Thank you for your question, you are relatively fine with Phenytoin and the seizure episodes in a form of lack of speech are the residue of a generalized type seizure. I don’t have a full description of your consciousness during the lack of speech episodes to decide whether this start is a partial epilepsy which can continue in a generalized or it is a generalized one from the first moment..
Avatar m tn Hello AB, welcome to the medhelp forum. Phenytoin can cause certain side effects like dizziness and mental confusion. Some people may also manifest incoordinate movements. Weight gain is not a documented side effect. It could be related to your alcohol consumption or wrong dietary habits and lack of exercise. An occasional one or two drink may be fine but moderate or large amount can cause significant increases in blood levels of phenytoin due to induction of hepatic enzymes.
Avatar n tn s going on here. Everything in the general chemistry is normal, with the exception of Folate is 35.66 and Cholesterol is low at 120. Is there reasoning behing the Folate being more then double what is normal?
Avatar f tn During those times I had not yet been diagnosed and was able to go back to life like normal, however after the diagnosis and being on phenytoin and switching to oxcarbazepine i am feeling awful. Dizzy, nauseated, moody, extremely tired, severe headaches that come and go. All i get from my Neurologist is these are side effects that will eventually go away. Because i never know when these symptoms will come on too strong I have missed a lot of days at work during my probation period.
Avatar f tn I totally forgot to tell you that he is on Phenytoin 100mg once daily. Can this be continued and taken for a long period of time? Thank you doctor once again for your immediate reply.
559053 tn?1274913374 There is a relationship between Folate and vitamin B12. Studies show that if the Folate is elevated it may be due to a vitamin B12 decreased. Suggest getting your vitamin B12 levels just to rule out any issues.
Avatar f tn Addition of other antiepileptic drugs like phenytoin,lamotrigene and sedatives will be helpful for controll of his night symptoms.
973741 tn?1342342773 Also, this is one of the problems that has been tied to the use of antibiotics and cortico-steroids adversely affecting beneficial flora, which also produce some of our B vitamins including folate. Buy the way, the real stuff is folate, folic acid is the synthetic supplement that if the body uses it well produces folate, I believe. Your son ever take a lot of antibiotics or steroids for anything when he was young?
Avatar f tn After that, the damage is usually permanent. Folate is trapped in an unusable form without enough vitamin B12 so you should see folate levels rise along with your B12 levels. If folate is still low, then supplement along with B12.
Avatar f tn all he said was that based on the folate being high he knew the b12 would be very low
1936411 tn?1333831849 ve heard of that might help with the itch are trying the over the counter antihistamines or antihistamine hydroxyzine (Atarax), anticonvulsants (e.g. gabapentin, carbamazepine, phenytoin), antidepressants (e.g. amitriptyline, paroxetine, mirtazapine), and even Pregabelin (Lyrica)....
Avatar f tn A few weeks ago I woke up with yellow crust on the corner of my lips and it went away in 2 days, and today I woke up and it's in the exact same spot again except a little more then before. It doesn't hurt or itch, it feels like my lips are very very dry. I don't smoke, I have grandmal seizures and my medication is phenytoin and kepra but I didn't read anywhere that would be a side effect so I'm worried this could be a STD or something.
Avatar f tn I am on a waiting list to see a doctor who may be able to help, but in the meantime have been treating myself with b-complex that contains methylated folate. I am taking an extra folate tablet too, so 1,400mcg altogether. I started on low dose aspirin, 75mg, as well. I have been taking the b-complex for about a month, but the extra folate and aspirin I started a week ago. I was previously taking 800mcg of folate.
Avatar n tn My lab results showed vitaminB12 - 297 Folate 11.3 I can not find an answer on any of the websites. What is the danger of 11.3 Folate and what can I do to reduce the numbers?
Avatar m tn And here's what I've read about these mutations -- they're very common but most physicians don't think they mean anything for most people. It's only those who manifest a problems that isn't dietary but from the mutation that need to correct for it. In your son's case, I assume the doctor found very low folate despite you feeding your son (and him eating) foods high in it.
Avatar f tn drugs like gabapentin, phenytoin are used for hemifacial spasm. Other options are botulinum injections and microvascular decompression surgery. Hope this helps. Take care.