Phenytoin and valproate interaction
Common Questions and Answers about Phenytoin and valproate interaction
dilantin
Thank you for your question, you are relatively fine with Phenytoin and the seizure episodes in a form of lack of speech are the residue of a generalized type seizure. I don’t have a full description of your consciousness during the lack of speech episodes to decide whether this start is a partial epilepsy which can continue in a generalized or it is a generalized one from the first moment..
Put this question again on the Doctor Forum, could she have had any reaction to the drugs she was given ask the Doctor who prescribed them all, sometimes they can react with each other.
Mirtrazipine and veneflaxine can cause seizures but it's rare. Zopiclone on the other hand could result in seizures if you skip doses. Zopiclone is usually used for short-term relief even tho it's not a benzodiazepine, it is quite the same procedure.
I have what my neurologist calls myoclonic jerks. I get them in my legs and back. I think they're from lesions in my spinal cord... (long story on that one - check my 'Spinal MRIs came back clean!' for details.)
Anyway, since I have leg weakness, I've decided not to take any drugs for the jerks, because it'll interfere with the strength of the legs, and cause drowsiness and fatigue - which I don't need!
Thank you very much for such a useful information. my son is having mix type symptoms. he is 9 yrs old. during siezers he does not loss consciousness. out of three EEG examinations reported slow wave formation in two reports and one is normal ,MRI is normal. The headache followed by aura remains for 5 to 15 minutes. it is happening 3 to 5 times daily.
Drug interaction of Claravis or Accutane includes tetracyclines , vitamin A-type drugs, vitamin A, and drugs that cause bone loss such as anti-seizure drugs such as phenytoin and corticosteroids. If you experience severe headaches and other symptoms like mood changes, muscle /joint pain or painful swallowing or peeling skin, it is best that you inform your doctor for proper management. Also when prescription medicine for migraine is not providing relief. Take care and do keep us posted.
These are anti-epilepsy drugs such as valproate, carbamazepine, lamotrigine, phenytoin, gabapentin, and pregabalin; muscle relaxants such as clonazepam and baclofen; tricyclic antidepressants such as carbamazepine, amitriptyline, and nortriptyline. The other option is surgery: Stereotactic radiosurgery, cutting or destroying part of nerve or removing blood vessel or tumor pressing it. If there is a tumor or blood vessel causing the symptoms then medical treatment will not help.
During those times I had not yet been diagnosed and was able to go back to life like normal, however after the diagnosis and being on phenytoin and switching to oxcarbazepine i am feeling awful. Dizzy, nauseated, moody, extremely tired, severe headaches that come and go. All i get from my Neurologist is these are side effects that will eventually go away. Because i never know when these symptoms will come on too strong I have missed a lot of days at work during my probation period.
For widespread or stubborn infections, itraconazole tablets have shown good results in curative aspects, but avoid its interaction with other drugs like antacids, astemizole, phenytoin and rifampicin. Most patient think the treatment has not worked if their pale patches do not disappear straight away. Please remember that the patches will take a long time to disappear and the treatment does not equate with disappearance.
Then, I went back on my Lyme Disease and Babesia (co-infection of Lyme) treatment (Chinese herbs), and they are worse than ever! I am hoping that this is just a bacteria die-off, which is common with Lyme, and your symptoms get worse before they get better.
Do you think I should increase my Toprol dose? I am seriously going crazy with all these PVC's!
This reaction is generally confined to the extremities but can affect the trunk and face and may be irreversible. Severe dermatologic reactions to phenytoin are infrequent. Some evidence, however, suggests that erythema multiforme is more likely in patients who undergo radiation therapy while receiving phenytoin.[22]
Lupus-like symptoms have been described for phenytoin. Whether phenytoin administration will exacerbate preexisting idiopathic systemic lupus erythematosus (SLE) is unclear.
Folic acid supplementation in folate-deficient patients with epilepsy changes the pharmacokinetics of phenytoin, usually leading to lower serum phenytoin concentrations and possible seizure breakthrough..."
It however says that initiation of Folic acid and phenytoin together is beneficial.
Since you can't go back and start all over again, you can take a small dose. It has been observed that as los as 1mg dose can perturb phenytoin’s levels, You may take doses lower than 1mg/day.
For widespread or stubborn infections, itraconazole tablets have shown good results in curative aspects, but avoid its interaction with other drugs like antacids, astemizole, phenytoin and rifampicin. Most patient think the treatment has not worked if their pale patches do not disappear straight away. They should be warned in advance that the patches will take a long time to disappear and the treatment does not equate with disappearance.
levothyroxine and insulin isophane (Moderate Drug-Drug)
MONITOR: The efficacy of oral hypoglycemic agents and insulin may be diminished by certain drugs, including thiazides and other diuretics, corticosteroids, estrogens, progestins, thyroid hormones, human growth hormone, phenothiazines, atypical antipsychotics, sympathomimetic amines, protease inhibitors, phenytoin, clozapine, megestrol, danazol, isoniazid, asparaginase, pegaspargase, diazoxide, temsirolimus, as well as pharmacologic dosag
I wanted to understand if he has to be cautious while using other drugs and what interaction Acitrom has with other drugs. He has been on Acitrom for a week now and has to use it for life.
Also, could you please provide me with any website that gives all possible information on Acitrom? I searched through Google but wasnt successful in finding the relevant information. I found this website...Your quick reply will be highly appreciated.
No. It would not worsen it long term. Valproate is a mood stabilizer and the other medication is an anti-depressent. Are you asking because his symptoms have gotten worse? On occassion an anti-depresent can worsen the symptoms of bipolarbut for other people they can be helpful but if there is a problem it would stop if the medication were changed. Speak to the psychiatrist about it.
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