severe depression, seizure ; bloody or tarry stools,
pancreatitis; confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling or high blood pressure. You can read more about this through this link: http://www.drugs.com/prednisone.html
If this persists, you can always discuss this with your doctor for an alternative drug that works for you.
I hope this helps. Take care and keep us posted.