[35,40] Most canine prostate cancers examined seem to lack receptors for male hormones, so it appears that unlike in humans these hormones are not responsible for the initiation or progression of prostatic cancers, but it is unclear whether castration is overall beneficial, neutral, or a risk factor
for their development.[30,40] Prostate cancer
is an aggressive cancer with a poor long-term prognosis.
Osteosarcoma is a bone tumor usually seen in large breed dogs.