My hands and feet are almost always cold (in
fact, they are right now), and I fall in
and out of relatively mild depression. I have been told that carrying the thalassemia trait has no obvious symptoms, but I've been poking around forums a little bit, and the symtoms I experience seem to be fairly common. I'm still looking for ways to lessen the intensity of these symptoms, but for me I've found that maintaining physical activity helps, as well as not oversleeping, or overeating.