Osteoarthritis and genetics

Common Questions and Answers about Osteoarthritis and genetics


Avatar n tn My neurologist has indicated further surgery is not an option and stated that research has been done and a genetic marker found for degenerative disc disease. Allele COL9A2. It has something to do with erradic bone growth (spurs etc). Have you heard of this, and is there research being done in the US? Also, he stated myelomalacia does not progress on its own, yet I find increasing weakness, with everything I do.
Avatar f tn * Right eye loss some degree of mobility (sixth nerve palsy) resulting in double vision * Noise inside head o Pulsating tinnitus (noise modulated by the cardiac pulse, with varying intensity depending on the day), probably due to cronic inflammation of some tissues inside the cranium) o Loss of hearing for frequencies higher than 8KHz - right ear * One EEG showed seizure activity, but I have not lost consciousness or blacked out ever * Periodic Numbness and weakness in left arm and t
Avatar f tn The clinical genetics department is the best for you and your brother to sort out how exactly it happened and who is a carrier and for whom dominant gene expressed in their body and this will make it easy for the treatment and future course of actions. You surely can carry a print out of this as this is just the knowledge what we have and some things are quoted from medical text books we follow.
7469840 tn?1409849436 So, this would be a link to cirrhosis and osteoporosis and osteoarthritis. I only gave osteopenia with regard to osteoporosis but also have osteoarthritis everywhere. I'd ask to have your levels checked before adding in a supplement though.
691233 tn?1228734020 Totally understand what you are going through. I myself have been in a few auto accidents and ten years ago I had 2 spinal fusions c3/c4 and c5/c6 within a year of each other. Recovered well and went on with my life. I also work in a classroom but as an assistant. Slowly as the years went on my life seemed somewhat normal. I continued to have numbness and aching in my left arm but was told it was nerve damage. My neurologist told me that it may never go away.
Avatar n tn I am off all anti-depressants and pain medications and feel like I'm slowly waking from a nightmare of doubt and un-certainty that was probably being caused by the drugs.
Avatar n tn But the DNA test was negative. I seem to have lots of the problems of the numb hands that lsat for weeks and I can't hold things when my hands are numb. You talk about these neuropathies being progressive. Can you say more? I know progressive means it will gt worse, but like how much worse? How bad does this get? The neurologist just shrugs his shoulders when I ask this. Also, when you say soemthing is slowly progressive, what does that mean? It takes months to get worse or what?
Avatar f tn Association analysis of polymorphisms in the DRD4 gene and heroin abuse in Chinese subjects. American Journal of Medical Genetics. 2000;96:616–621. Lotsch J, Skarke C, Grosch S, Darimont J, Schmidt H, Geisslinger G. The polymorphism A118G of the human mu-opioid receptor gene decreases the pupil constrictory effect of morphine-6-glucuronide but not that of morphine. Pharmacogenetics. 2002;12:3–9. Lotsch J, Zimmermann M, Darimont J, Marx C, Dudziak R, Skarke C, et al..
Avatar n tn For the last 6 months I have been getting tearing (look like paper cuts) in my vaginal area (1/4 to 1/2 inch long). I get the tears at least once or twice a week and they last from 2-4 days, go away for a few days and then come back. They continue to occur in the same locations; 1. Inside the vaginal lips on the sides almost always in the crease (between the labia minora and majora?) 2. Between the anus and vaginal opening (perineum) 3. Above the clitoris in the "hood" area.
Avatar f tn Osteoarthritis is not the same as "Rheumatoid" arthritis. I'm 52 and had a total rt. knee replacement at 42, and the other knee a partial replacement three years ago. The rest of my bones, head to toe are affected as well. Rings don't go over my knuckles anymore etc. It is genetics. Some people are just programmed this way. Ask your GP to refer you to a NEW RHEUMATOLOGIST (young with current information) or at least get ask about taking an Anti inflammatory.
Avatar f tn I am 25 years old and am being treated for osteoarthritis (fingers, knees, elbows and toes) and mild fibromyalgia. A friend of mine told me about the hypermobility type of EDS. I do have loose ankles that like to give out on me, flat feet, easy bruising, scoliosis, irritable bowel syndrome and hyper mobility in my toes, elbows, fingers and thumbs (they extend farther than they should). However, my skin is not elastic or velvet like. Could this be EDS even without the skin abnormalities?
886824 tn?1253740254 http://AccessDNA.
921323 tn?1268679412 Some say, why don’t we save the millions of dollars spent on drug research and instead invest them in education, legislation, and regulations that will help us eat better and exercise more? Put the money towards the health costs of the uninsured. Or, use it to fund research in diabetes, heart disease, or any of the other countless complications of obesity. But is it too early to admit defeat?
521161 tn?1212369304 These include...
931217 tn?1283484935 Neutering involves removing the source of the hormones that control reproduction and that determine the typical physical and behavioral characteristics that distinguish males and females. In dogs and cats, this is usually done by surgically removing the testicles in males (castration) and the ovaries in females (spaying). In the United States, the uterus is typically removed along with the ovaries in females, and virtually all dogs and cats are spayed or castrated.
Avatar n tn Hi all. New to this. I am a 44 year old woman who is physically fit (gym 5 days a week) and eats pretty well. Approx 5 weeks ago I developed veins showing on both hands. They have not gone away and infact they are bulging most times, and I can "feel them". They have increased and I can see some starting to climb up my forearm now. Before this, my veins barely ever showed.
211940 tn?1267884866 However, he said it could NOT be causing me so much pain. He checked out my arm and noticed a hard soft tissue knot, and suggested removing it through surgery and it "might" relieve my pain. So, 3 weeks ago I had the said surgery and it was removed (a hard soft tissue mass about the size of a marble). No, this was not the cyst inside my humerus bone. Anyways, I still have the pain, and it is extremely terrible at night (on a scale of 1 to 10, a 20 at night).
552681 tn?1215136132 The numbness continued to the point that I lost use of the arm and it extended down into my right foot and leg and eventually into the right side of my face. Thinking that I was experiencing a stroke, my primary MD transferred me to a larger hospital where I underwent an MRI of my Head and Carotid U/S, and nothing was found at that time that could explain what was happening to me.
Avatar n tn Well, Sjogren's is believed to have a genetic component, and believe me, my whole family has got the symptoms and are now being tested. There's nothing to be done yet about genetics! The second component is supposedly a viral infection, and I agree with that too. Mine started a couple months after I got Mono. I like the idea that something could get my immune system to calm down, but looking at my family, I don't think it's likely.
Avatar f tn First, I'm 47 and a single mom of 4, 2 boys, nearly 11 and nearly 15, and 2 girls, 12 and nearly 18. My life was busy and fulfilling. I worked full-time as a court reporter in Superior Court and loved it. I'm the oldest of 3. My parents are originally from Ireland. My mom passed away in June 2006 at the age of 82.
975514 tn?1325001538 I wasn't able to add additional lines to include them all, but I thought this might bring up a good discussion in this group about genetics and how these things affect those of us who have FM and CFS. I am eager to hear everyone's comments.
Avatar m tn •Various types of arthritis, such as rheumatoid arthritis and osteoarthritis •Jaw injury •Long-term (chronic) grinding or clenching of teeth •Certain connective tissue diseases that cause problems which may affect the temporomandibular joint
Avatar n tn Long distance runner, amatuer body builder, and martial artist. I am not heavy and I do eat well. I have the genetics to be predisposed to stroke and high BP. Two years ago I woke up and found it almost impossible to move my right leg. That was when I was diagnosed with the DDD and spinal stenosis. It was suggested that I have back surgery. I refused and opted for spinal epidurals (3 of them).
Avatar f tn I seem to have got the short end of the stick genetically in my family. My mother had extremely bad osteoarthritis starting in her mid-forties. She suffered for years and years and had it everywhere. I have had a similar course where I've had arthritis (though minor) since my twenties. It was bearable then and only flared up once in a while. But it started getting really bad in my late thirties. I tend to be prone to gaining weight like she was, too.
Avatar f tn I have several chronic health conditions acquired since my 30s; including early-onset osteoarthritis of the sacral spine and other joints, plus digestive issues. Thank you.
1793142 tn?1315382976 I did forget to mention, that I too have fibro, with my lupus, I also have raynauds, neuropathy, deteriorating disc disease in over half my spine, I have osteoarthritis in my left hip and knee, daily muscle cramps and spasms GERD, IC of the bladder, anemia, photo sensitivity to sun and ultra violet lighting, I have had retina bleeding in my left eye and loss of vision caused by permanent damage to the blood vessels in my left eye.
Avatar m tn Hepatitis c positive and HIV/AIDSin children and adult, What are the available management options and which is the best that is acceptable practise?
Avatar m tn The problem is that you're dealing with a medical system that operates and thinks inside a box. Even the more open and progressive conventional health professionals, still have to abide by a set of rules, procedures & protocols imposed by the governing medical boards. And this is what might be working against you. For example, your hypothyroidism regulation is possibly not effective. Your reverse T3 (rT3) if tested, will probably show higher levels than normal.
Avatar n tn When did you begin Atkins and lose the weight?Do you have any spots of osteoarthritis? Garden variety arthritis also know as Degenerative Joint Disease? The pain and tingling that you describe is likely neuropathic pain. It is difficult to treat, but there some things that work with some people. But before anyone jumps to the conclusion that your Diabetes is at fault (and it likely is) you deserve a workup for peripheral neuropathy.
469720 tn?1388149949 As you may have noticed by now, the focus of this forum is cardiovascular disease(CVD) prevention. The statistics speak for themselves. CVD is the leading cause of death in the US and worldwide. Although we have made substantial progress in the development of medications to combat the causes of CVD like high cholesterol, hypertension and diabetes; the rapid proliferation of these diseases virtually negates and medical benefit. In other words, we are treating the consequences, not the cause.