Anthelmintics, such as mebendazole, pyrantel
pamoate, and albendazole, are active against Enterobius vermicularis (pin worm). Itching, irritation, and excoriation should be treated symptomatically. Reinfection with E vermicularis immediately after the completion of drug therapy is common. Additionally, young pinworms may be resistant to drugs. Successful eradication of pinworm infection requires at least 3 doses of medication, separated by 3 weeks.