Niacin and fibrates
Common Questions and Answers about Niacin and fibrates
niaspan
High cholesterol runs in my family so even with diet and exercise my numbers are still a little high. I started getting heart palpitations a few years ago and after a lot of testing was told they were harmless PVC's/PAC's. Well, I stoped taking my Tricor and Zocor for a few months and my heart palps were gone. The problem is that my cholesterol numbers went back up. I started back on the statins and low and behold the palps returned.
According to Uptodate, the medications that cause this condition include colchicine, nondepolarizing muscle relaxers with high doses of corticosteroids, antimalarials, niacin, penicillamine, fibrates, zidovudine and statins. Drugs that can cause elevated liver enzymes include cocaine and alcohol, particularly when they are abused.
Testing patients for elevated muscle enzymes helps doctors determine the cause and can help to evaluate muscle pain, weakness and inflammation.
http://www.nhlbi.nih.gov/health/prof/heart/other/accord/q_a.htm
"ACCORD will continue to study the effects of intensive compared with standard treatment of blood pressure and the effects of fibrate plus statin compared with placebo plus statin."
That is from the National Institute of Health, which is in the federal government, not some outdated info from a private website like rxlist.com that is not accountable to anybody.
Factors that elevate HDL concentrations include chronic alcoholism, treatment with oral estrogen replacement therapy, extensive aerobic exercise, and treatment with niacin, statins, or fibrates. On the other hand, smoking reduces levels of HDL cholesterol, while quitting smoking leads to a rise in the plasma HDL level. HALP from genetics is considered primary and HALP resulting from environmental issues is considered secondary. HALP is more prevalent in women at a rate of 7.
if you can try the slo release formula and make sure you take with food.. I use and research a lot of alternate treatments.. Niacin has the propensity to flare up causing those exacerbated feelings also your scalp may feel like its on fire too.. You should be ok and if it doesn't go away seek medical treatment ..
Did you have a question on adult type 2 diabetes?
Call it mind over matter or whatever but I started taking Niacin and inositol last week. I have felt a steady improvement in my mood and anxiety levels each day.
I have been taking a B Complex, 100 mg everyday for the past 2 months. The Niacin I take is 400 mg so that is a 500 mg/day dose. Yesterday I bumped up to 400 mg in the AM and 400 at night. There is definely an improvement that I feel. i am not 100% yet but I feel better than I did a week ago.
Niacin in most people causes the face to flush/blush. No flush Niacin is readily available OTC. A word of caution, however, Niacin is a B3 and B3's are known to elevate blood sugars. Test your bs often and on a regular basis.
using statin drugs) because Niacin also raises HDL and cuts LPa and triglycerides (while statins only cut LDL). I have been on this regimen since 2003 and the effect on my cholesterol/triglycerides and LPa has been more than as hoped for. Just as with statin drugs, it is necessary to get regular blood tests (ideally every 6 months) to ensure there is no liver damage.
3 oz, 7.8 mg
Daily Value: 49%
Just under 50 percent of the day’s niacin in a three-ounce serving.
Tuna Packed
in Water,
Niacin Content: 3 oz, 8.6 mg
Daily Value: 54%
Canned tuna is the best source of niacin, and it’s packed with docosahexaenoic acid, a type of omega-3 that stunts the growth of belly fat cell. Canned chunk tuna is considered a “low mercury fish” enjoy two to three times a week, according to the FDA’s most recent guidelines. I don't trust the FDA!
What is the purpose of the
“No-flush” niacin preparations, such as inositol hexaniacinate and nicotinamide, are widely sold as niacin alternatives that do not cause hot flushes. In my experience, however, they simply do not work. In other words, no flush, no effect.
The correct dose of niacin depends on what abnormality you and your doctor are trying to correct. To raise HDL and correct small LDL, a dose of 750-1000 mg a day usually provides full benefit.
So, make sure you run everything by your doctor and come up with a mutually agreed upon plan. Niacin HAS been used to lower triglycerides and raise HDL (good) cholesterol. Improving these two aid in overall improvement in total cholesterol numbers. But niacin can have real draw backs too. You MUST talk to your doctor before starting a niacin supplement in my opinion. And if you are on a cholesterol lowering medication already, it may have no effect at all.
You don't say what your LDL lipid levels are? however your total cholesterol level isn't too bad.
Your HDL is a bit on the low side but there are ways to boost this and exercise is one way.
Your triglycerides are very high. Do you have a lot of sugar in your diet?
I'm not sure if you need statins, but there are medications to lower trigs which I believe are called fibrates and these also raise HDL.
I was told from friends that Niacin helps as well as fish oil. So, over the past 8 mths I took Niacin and fish oil and my new blood draw cam up with a perfect score in the cholesterol area but my Bilirubin total was elevated at 1.4, Iron UIBC low at 102, Iron serum high at 175 as well as Iron Saturation at 63, and my biggest concern was my TSH high at 5.08. I do not have any symptoms. I just received the second blood draw for a possible job in Antarctica.
I am bipolar and have taken niacin for years....I took 500mg of niacin the reagular kind not the no flush kind It did cause me to have a niacin flush (which is typical)...it has never caused me trouble with mainia only made me flush wich eased anxiety and caused me to be tired afterwards...It might affect others diffently though. Nician is a B vitamin and B vitmins can cause you to more energetic you shouldn't take them in excess esp if you have bipolar....
Niacin is essential to a healthy diet but too much can cause you to turn bright red, hot and itchy. It's usually found in such low doses in foods, that it won't happen unless you take niacin tablets directly, and too many of them.
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