Mycophenolate levels

Common Questions and Answers about Mycophenolate levels

cellcept

Avatar m tn If suppressants are at the correct trouph levels, say, Prograf and Rapamycin, what are the next steps - switch suppressants, treat?
Avatar m tn I am being successfully treated for a rare autoimmune condition with 15 mg prednisone and 1 gr mycophenolate daily. Although mycophenolate use involves a risk of opportunistic HSV infections, I was not warned about this. I recently had sex WITH A CONDOM with a partner whose status for HSV infection is unknown. Within about a day, I had developed numerous lesions. These spread rapidly and my doctor said they had an appearance consistent with HSV.
778275 tn?1326913623 I can sort of answer your first question. Mycophenolate mofetil (MMF) or Cellcept has been extensively researched for its use in myasthenia gravis. Also, it carries a FDA black box warning that it may increase your chances of infection, lymphoma and congenital malformations (for pregnant women). Also, its optimal dose is yet undecided. Pyridostigmine (Mestinon) is the usual first line treatment for MG.
Avatar n tn We converted 20 patients from azathioprine to enteric-coated mycophenolate sodium (EC-MPS) and continued the remaining 15 patients on azathioprine. Exploratory mRNA expression profiling, performed on five randomly selected EC-MPS patients, revealed significant upregulation of neutral endopeptidase (NEP), which is an enzyme that degrades angiotensin II.
1054753 tn?1339968724 i do not think that the loose bowel movements are directly related to the transplant itself. they could be from the medications such as mycophenolate or ursodiol. sometimes certain infections can also contribute. If the liver tests are OK, then the loose bowel movements are not from the liver.
Avatar m tn My doc is trying to reduce the dose. Since I was on tacrolimus only(as Mycophenolate causes TLC to go down in two occasion), sirolimus 1mg is started along with reduced tacrolimus(2mg BD, Tac level ~4.5). But the creatinine is still high(1.8). It seems some side effect of Sirolimus is also coming as the TLC is 3400 and platelet is 80,000. What do you suggest to bring creatinine under control? What is the way to determine the exact required dose of tacrolimus?
Avatar m tn The standard therapy options include intravenous immunoglobulin and plasmapharesis, corticosteroids, azathioprine, cyclophosphamide, etanercept, mycophenolate mofetil, interferon alpha 2a and tacrolimus. Current ones are interferon beta 1a, rituximab, and high dose cyclophosphamide. Your neurologist needs to apprise you of the long-term side effects since prolonged therapy are required. Botox shots are not known to be used in therapy.
Avatar f tn Hi all My wife has SLE which about 8 months ago began to come undercontrol with mycophenolate.
Avatar f tn t respond to prednisone or azathioprine, your doctor may prescribe stronger immunosuppressants, such as mycophenolate (CellCept), cyclosporine (Neoral, Sandimmune, others) or tacrolimus (Prograf). --------------------------------------------------------------------------------------------------- When medication fails to stop the progression of cirrhosis eventually a liver transplant must be considered. This is another reason to also seek treatment with a transplant facility.
Avatar f tn And immune suppresant mycophenolate for 6 months. I am grateful for your thoughts. Apologies in delay replying I have been unwell.
Avatar f tn I am not on Cellcept which is Mycophenolate Mofetil 1g morning and 1g night. This is a fantastic immunposuppressant. Basically what I am telling you is that at any time your body cannot any longer tolerate one drug, there is always another waiting. The one I am on now is more 'pure' in other words there are less chemicals in in to effect the liver. It might be worth a mention if you are uncertain but many people are able to tolerate your medication for many years.
Avatar m tn however, there is no documented increased cancer risk specifically with the use of long-term mycophenolate use. the less immunosuppression one takes over time, the better however.
Avatar m tn I currently am on 5 mg of prednisone and 50 mg of Imuran. I get checked now every 6 months and everything is back to normal levels except my bilirubin is slightly out of range but doc doesn't feel its an issue. I have been experiencing a little bit of joint pain in my back and knees when I get up in the morning. Thinking this is because I don't exercise enough or just getting older! Any thoughts on this would be appreciated.
422425 tn?1307992990 Billydude and cudagirl: I did some research, and "grade" does play into diagnostics of T-cells and auto-immune related conditions. It appears from what I read to be used most often with cancers and HIV but can be used with any auto-immune condition. What I could not find was a chart of what was a bad or good level. Without that kind of comparison, it's like not knowing anything at all. Billydude: You said that you take Cellcept/Mycophenolate for Sjogren’s?
Avatar n tn Also, I have IgA nephropathy and have been on low dose immunosuppressant (mycophenolate mofetil 250 mg twice daily) for the past 1.5 years. 4 days ago, I noticed a little bump in on my labia minora. and I thought maybe it was a boil and tried to break it. It is now pus filled and looks like a zit. its just the one. I have no tingling or itching tho there is some pain now after i messed abt with it which is kinda like the pain i feel with zits anywhere.
1323747 tn?1364806882 It can get better as thyroid levels improve .........Free t3 levels are the key sometimes, upper third of range. Magnessium too.
Avatar f tn Corticosteroids ≥20mg (0,5mg/kg) prednisolone (or equivalent per day for more than 4 weeks Corticosteroid dose of ≥5mg prednisolone (or equivalent) per day for more than four weeks plus at least one other immunosuppressive medication (e.g. azathioprine, mycophenolate, ciclosporin) or rituximab within the last 12 months.
Avatar f tn I don't believe that OH is treating with a PI. The PIs can increase plasma levels of tacrolimus and cyclosporine very significantly - to toxic levels. There's a lot of research regarding dosing that needs to be done before these drugs will be used in the transplant population.
4848471 tn?1372238752 I was JC+ before I even started Tysabri and am about one and a half years into it now, still taking it..............I talked to the Tysabri regional rep about it and they still feel our chances of PML are very low.
Avatar n tn I am on 750 urso three times a day now.. I am 52. I am now on Cellcept (mycophenolate Mofetil) 1g twice daily. This is because the other meds like Azathioprine and Mercaptopurine disagreed with me intensely and I turned a beautiful shade of butterscotch and was oh so ill. This new drug has less chemicals in and suits me very well, in fact I walked 6 miles in Jordan as opposed to not even being able to get out of bed.
1837090 tn?1328040121 ) but besides all this lol they took my hcg levels again they were 575 on January 8th and yesterday( jan 21st) they were at 61000 so I'm just wondering as I still don't know how far I am haha anyone have a number close to mine and if so how far we're you :) thanks ladies
Avatar f tn I have felt awful for some time now and seem to have so many thyroid symptoms. My levels of tSh have always been 1.2, 2.3... Last year I was feeling awful and it was up to 4.5. My doctor did not see this as a big deal. I am once again feeling INCREDIBLY anxious, not sleeping, hoarse, .... The list goes on... Went for bloodwork yesterday. TSH is 3.7 and Free T4 is 1.2. What does this mean? My mother had thyroid cancer a couple of years ago and had hers removed.
Avatar n tn My hcg levels yesturday where 124 and when I I took the pregnancy test it said 1 - 2 weeks. I just took another Clear Blue now and it says 2 - 3 weeks. I take it that would mean my levels where going up. I know I have to wait till I have my bloods done tomorrow but I was thinking this is good sign. What do you think.
Avatar f tn my levels are ast28 and alt is 21 was just taken off medcine after 2 months body had a complete breakdown of my platelets were down to 26,red and blood counts were also at a critcal levels my platets are now at 60 what do you think?