mycophenolate for lupus

I can sort of answer your first question. Mycophenolate mofetil (MMF) or Cellcept has been extensively researched for its use in myasthenia gravis. Also, it carries a FDA black box warning that it may increase your chances of infection, lymphoma and congenital malformations (for pregnant women). Also, its optimal dose is yet undecided. Pyridostigmine (Mestinon) is the usual first line treatment for MG.

recently diagnosed of sle with lupus nephritis type v and is currently on omnacortil(prednisolone) 40mg/day and chloroquine at 24 yrs of age now ive started to notice my moon like face after 2 weeks and its getting wierd and wierd.is there any way to be out of my new face ...

I am now on valacyclovir for prophylaxis and supression, because I must continue mycophenolate use. Of course, there is no point in doing this if I do not have a latent HSV-1 or HSV-2 infection. On the other hand, I am reluctant to allow a recurrent opportunistic infection. Moreover, I have a regular but intermittent partner who I have informed about these developments.

Thanks for the feedback. I do have lupus nephritis, and have had this disease for 3 years now. Do you think it's the lupus that's triggering this numbness in my right side. And also the doctor told me that it couldn't be my lupus. I'm just concern and need to know the next steps that i should take when i go see my doctor and also i will get a second opinion.

however, there is no documented increased cancer risk specifically with the use of long-term mycophenolate use. the less immunosuppression one takes over time, the better however.

And immune suppresant mycophenolate for 6 months. I am grateful for your thoughts. Apologies in delay replying I have been unwell.

My doc is trying to reduce the dose. Since I was on tacrolimus only(as Mycophenolate causes TLC to go down in two occasion), sirolimus 1mg is started along with reduced tacrolimus(2mg BD, Tac level ~4.5). But the creatinine is still high(1.8). It seems some side effect of Sirolimus is also coming as the TLC is 3400 and platelet is 80,000. What do you suggest to bring creatinine under control? What is the way to determine the exact required dose of tacrolimus?

Billydude and cudagirl: I did some research, and "grade" does play into diagnostics of T-cells and auto-immune related conditions. It appears from what I read to be used most often with cancers and HIV but can be used with any auto-immune condition. What I could not find was a chart of what was a bad or good level. Without that kind of comparison, it's like not knowing anything at all. Billydude: You said that you take Cellcept/Mycophenolate for Sjogren’s?

I have been having electrical shocks in my left calf now for about a year and a half. After this diagnosis I was told to continue with my Gabapentin {3x a day @300mg} but I was also told that a possible Botox shot in the surface area of my left calf might also end this pain. Can anyone tell me what possible effects the Botox shot might have on me such as adverse reactions etc.

i do not think that the loose bowel movements are directly related to the transplant itself. they could be from the medications such as mycophenolate or ursodiol. sometimes certain infections can also contribute. If the liver tests are OK, then the loose bowel movements are not from the liver.

additional agents such as mycophenolate (cellcept) may be necessary or in cases of severe rejection a medication such as thymoglobulin may be needed.

I am a newly diagnosed lupus patient but have been told there is no lupus involvement. I received IV steroids for a couple of days for my lupus and I noticed a change in my eyesight. (better) I was put on 20mg of prednisone for 1 1/2 months and then I was put on 40mg prednisone for a week. I noticed that my eyesight was getting better. Personally I dont know if my eye problems have anything to do with the lupus.

s 52 years old and has had discoid lupus (lupus erythematosus discoides) for 7 years now. Naturally, since it's an autoimmune disease, she's worried about whether she can get vaccinated against COVID19 or not. She had asked one doctor (not an immunologist though) but he hasn't given her a clear answer. She also has not been able to reach an immunologist since it's hard to reach doctors for non-emergencies or non-COVID issues anywhere now.

I was just recently diagnosed with lupus after having symptoms for 8 years. Yesterday the glands under my chin (on each side of my throat) have swollen up. The right one is bigger. and my throat is very sore. Is this a problem with lupus or is it just something like allergies. I wouldn't even be wondering about it, but I haven't even been sneezing so far this year with the pollen (very unusual). Just wondering.

Hi all My wife has SLE which about 8 months ago began to come undercontrol with mycophenolate.

Does anybody know what a biopsy for lupus would show? I had a sun spot biopsied and the GP noted I had a possible autoimmune rash ( I have a malar rash) and the pathologist said I had chronic inflammatory cells around the subepithelial connective tissue. I have had high ESR and CRP, low iron, elevated liver enzymes etc and have responded to prednisone but need an official diagnosis. What would rosacea histopathology show up as?

Last year I was diagnosed with Rheumatoid Arthritis and started a trial of a DMARD. I do seem to be less stiff in the morning. However, I still have severe fatigue and soreness. Lupus runs in my family also, but I was negative on ANA tests. Since I know MS is related to both Lupus and RA, I looked up the symptoms. I frequently am lightheaded and difficulty focusing my eyes.

t know if the rheumatologist would do just blood tests to see if you have an autoimmune arthritic rheumatoid arthritis, gout, lupus) problem or whether he also does xrays to show up degenerative changes in the bones (osteoarthritis). As you had blood tests done, I presume your blood levels were fine? Best wishes.

I have interstitial cystitis and a couple other autoimmune disorders. I've been tested for lupus, rheumatoid arthritis and sjogrens several times in the last 7 years but they've been negative. I have very dry eyes, some joint pain and ulcers that come and go in my throat (just beyond the tongue), and have lost my energy, always tired but do not sleep well. Is sjogrens tough to diagnose through bloodwork? I'm tired of all the doctors and they probably feel the same way! Help...

I've had 2 strokes and tested positive for the Lupus Anticoagulant. Is Coumadin the best or only option for this? Are Plavix or Aggrenox Options?

I have been taking predisone and mycophenolate for the past 9 yrs and until the biopsy I thought everything was status quo. Again thank you for all the information.

i am still waiting for my lab results, so i am not on any medications for lupus as of yet. i do take hydrocodone for my severe back issues, and even thats not helping with the pain today!!!! do you think there would be any benefit for me to go to the emergency room?? i mean, what can they exactly do for me??? i don't have a lupus dx as of yet, but it looks like the doc is leaning that way for sure.

I have auto imune hep I have had it for 5 years I keep really good health and work full time I am on Azathiropine 50mg in the morning and 25 at night.

- Extreme fatigue (tiredness) - Painful joints. - Abnormal blood clotting ( lupus anticoagulant positive ) Blood tests: - I had 2 positive ANA during the time ( both 1:100 speckled pattern, last one negative in september after 1 week off sun exposure ) - anti-dsDNA - negative My rheumy didnt given me any treatment till now, nothing at all. Please tell me your opinion....is Lupus or not? Thank you !

She sent me for a spinal tap. They checked me for MS, lupus, limes, and a bunch of other crappy illnesses. The test for me came back negative. There were 5 panels they did with the spinal fluid. The spinal tap was a very easy procedure, no pain, in and out, however I ended up needing a blood patch to fix the puncture spot and that my friend was the most painful thing I've ever had done.

As noted above, the treatments for Lyme and lupus are disparate. In lupus, an overactive immune system needs to be controlled, whereas in Lyme, the immune system needs to kick into overdrive to fight an infection. I 2nd patsy10's comment, I've also read ppl who had positive ANA from Lyme. I never did. I did have a high SED rate and a butterfly rash that looked like lupus, but it was Lyme.

Mycophenolate for lupus

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