multiple sclerosis onset of

Defining the clinical course of multiple sclerosis: results of an international survey by Fred D. Lublin and Stephen C. Reingold for the National Multiple Sclerosis Society (USA) Advisory Committee on Clinical Trials of New Agents in Multiple Sclerosis. In Neurology. 1996 Apr;46(4):907-11. http://www.ncbi.nlm.nih.gov/pubmed/8780061 Anyway, up until that point clinical trials were hampered by a lack of agreement on the types of MS and the definitions of those types.

I just received this abstract the other day via email, thought I'd share in light of the current discussion re: 'benign' MS. For the purposes of this study, it apears that >10 yrs following disease onset with no or minimal disability was the criteria for mild/benign MS.

Approximately 50% of patients with RRMS convert to Secondary Progressive Multiple Sclerosis (SPMS) within 10 years of disease onset. After 30 years, this figure rises to 90%. At any one time, the Relapsing-Remitting form of the disease accounts around 55% of all people with multiple sclerosis. SPMS is characterised by a steady progression of clinical neurological damage with or without superimposed relapses and minor remissions and plateaux.

http://www.medhelp.org/forums/Multiple-Sclerosis/show/41 Specifically, this Health Page describes the lesions found in MS: http://www.medhelp.org/health_pages/Multiple-Sclerosis/How-MRIs-Show-Lesions-in-MS/show/23?cid=36 Also, what a typical MS work up entails: http://www.medhelp.org/health_pages/Multiple-Sclerosis/Common-Blood-Test-Youll-See-During-the-Diagnosis-Process/show/446?cid=36 Good luck and keep us posted.

Long-term follow-up of benign multiple sclerosis in Hordaland County, Western Norway Abstract Objective To study the frequency of benign multiple sclerosis (MS) after 20 years disease duration and identify early clinical and demographic prognostic factors of a benign course. Methods A population-based cohort including all 230 MS patients with clinical disease onset during 1976–1986 in Hordaland County, Western Norway was followed up with clinical examination in 1995 and 2003.

Late onset multiple sclerosis (LOMS), defined as the first presentation of clinical symptoms in patients over 50, is not a rare phenomenon as previously thought, since the prevalence ranges between 4% and 9.6% in different studies. The course of the disease is often primary progressive and pyramidal or cerebellar involvement is observed in 60%-70% of the patients at presentation.

//www.medhelp.org/health_pages/Multiple-Sclerosis/Relapses--Pseudo-Relapses-and-Remissions/show/372?cid=36 http://www.medhelp.

Seizures have been observed before and presumably marking the clinical onset of multiple sclerosis, and during acute bouts of MS. In some cases, seizures appear to be the only sign of a flare of MS. But there isn't general acceptance of seizures as the first and only sign of MS.

In a second study with a 5.6-year follow-up of 74 patients with optic neuritis, 22% developed clinical multiple sclerosis (Jacobs et al 1997); 76% of these had abnormal MRIs initially. Of note, half of the patients who did not develop clinical multiple sclerosis also had abnormal MRIs at onset. In a third study, optic neuritis with no MRI lesions led to multiple sclerosis at 5 years in 16%, versus 51% of patients with 3 or more MRI lesions (Beck 1997).

but in some cases, the clinical symptoms appear first. It is estimated that 5 - 8 % of people have a clear MRI at the time of appearance of clinical symptoms or diagnosis. These many people will continue to have a clear MRI. If there is no MRI finding for two years after the diagnosis, the diagnosis should be revised. A person with multiple sclerosis is going to have lesions on the brain. The MRI, though most effective currently, may not pick up some lesions.

These palsies are often caused by diabetes, but can also be the result of a head injury, tumor, multiple sclerosis, meningitis, high blood pressure or an aneurysm. The diplopia is usually resolved when the underlying condition is treated but some people may require additional help such as vision therapy, special eyeglasses or surgery. http://www.eyedoctorguide.com/eye_problems/double_vision_diplopia.

Everything seemed minor until the last line, which raised the possibility of demyelinating process, including but not limited to entities such as multiple sclerosis. Please follow-up with your neurologist for further workup and/or evaluation.

relationship between seasonal variations of relapse and age of onset (http://www.ncbi.nlm.nih.gov/pubmed/8407141). This is from 1993, but they hypothesize that "the fall in melatonin secretion in the spring may account for epidemiological findings revealing a high incidence of relapse of MS in the spring." Seasonal patterns in optic neuritis and multiple sclerosis: a meta-analysis (http://www.direct-ms.org/pdf/VitDMS/ONMSonset.

I have had increased symptoms of fatigue and in recent weeks a tingling along both of my legs, my feet hurt and I am having alot of back pain that sort of circles around. Should I start with my PCP to see if it is my back or go straight to my neurologist? I am on Copaxone, but I was off of the shots for 6 mos prior to this last MRI for insurance reasons.

You would benefit from seeing a neurologist. You need a complete work-up to determine the cause of your neurological symptoms. The neurologist should do lots of blood tests to help them figure out what it is and run other tests to determine the cause of your neurological symptoms. Because you have had so many viruses, my guess is that you have an autoimmune disease.

The cause of meralgia paresthetica is compression of the nerve that supplies sensation to the skin surface of your thigh." https://www.mayoclinic.org/diseases-conditions/meralgia-paresthetica/symptoms-causes/syc-20355635 If it's possible i'd get it seen by your family dr, the odds of this type of situation being the first presentation of a neurological condition like MS is very unlikely. Hope that helps.....

He had an MRI of the brain that showed multiple foci of T2 and FLAIR hyperintensity in the white matter of both cerebral hemispheres including approximately 5 small lesions in the periventricular white matter, lovated at the callosal sptal margin and oriented perpendicular long axis of the lateral ventricles. THere are 2 Flair hyperintense lesions along the undersurface of the copus callosum. Focus of T2 hyperintensity is seen in the deep white matter of the right frontal lobe.

If not, I urge him to get started on one of those asap. They do not cure MS but they have good results of slowing down the progression. He may also be on some other drugs for his symptoms. Is he? I ask because some drugs have side affects that affect you sexually. This could be one of his problems or it could be something else. I am no doctor and as wobbly did, I urge you to have your bf address this with his doctor.

Also after my delivery I had problem of DVT. What is the cause of DVT? Is it related to MS? I was admitted in the hospital for 15 days.

m new to this forum and just had a couple of questions regarding possible MS diagnosis. In July of 09 I had a MRI of my brain which showed a left frontal lesion measuring 1.4 x 1.2 x 1.4 cm. I had another in August 09 which measured the lesion at 1.0 x o.6 x 1.2 cm. I also had a third one in August 09 which showed another decrease in size. (sorry don't have those results in hand). My neurologist impression is ( Solitary focus of demyelination left frontal brain unclear etiology).

my sister (24) was diagnosed Multiple Sclerosis in 2010, responded to steroid. now she suffered sudden & complete loss of vision in her left eye. she has been put on SOLUMEDROL. please suggest any available treatment modalities world over ? chances of return of vision ??

You mentioned there are things I can do to improve my condition. Could you give me the details? I have been out of the hospital since 4/27/12 & continue to have off and on periods of the same symptoms that I went in with including loss of appetite & weight loss of 7lbs. I was 422 lbs on 4/28/12 & this morning I am 415lbs. This is not a bad thing for me since I am obese. I am concerned about nutrition.

Multiple sclerosis onset of

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