When attacks of pain cause considerable disturbance with life activities, a decision has to be made whether to cut the
sphincter (sphincterotomy), during ERCP. When
sphincter of Oddi manometry has confirmed that the pressures are high, sphincterotomy gives good relief in most patients (but not all). The performance of sphincterotomy carries a risk of complications, such as bleeding and perforation, in addition to pancreatitis.