It won't hurt you to take the two opiates together, they are often prescribed together for pain control, with one being used as the primary med and the other being used for breakthrough pain. The problem with it, though, is you have GOT to watch your tylenol consumption. The safe limit of tylenol per day is 4000mg, anything more than that can be toxic, and since both meds contain tylenol, you'll reach that level fairly quickly without half trying.