Metformin and renal function
Common Questions and Answers about Metformin and renal function
glucophage
I am maintaining a stage 3 and was on a 3 month regiment of vitamin d and we also eliminated metformin. I take Amaryl now, instead.. My blood glucose was out of control but my PCP put me on Victoza. That seems to be helping with the exception of BS levels being very low in the morning. My PCP has suggested she might take me off the Amaryl and just have me take more insulin along with the Victoza and Januvia. At this point we're experimenting with the meds to see what works better.
I am not aware that impaired renal function precludes treatment for HCV. I have read that kidney disease is a negative predictor of SVR but, so too are a lot of conditions yet people have overcome them. I have seen articles which discuss the plasma levels of ribavirin with renal impaired patients. The suggestion is that rather than weight base dose these patients the dose should be arrived at by considering GFR (glomerular filtration rate).
This is from Clinical Care Options @ http://tiny.
The blood urea nitrogen or BUN test is primarily used, along with the creatinine test, to evaluate kidney function. Those with advanced cirrhosis may have an impact on kidney function as their liver function progressively fails. This is why the creatinine level is one the the blood tests that make up the MELD score that determines the need for liver transplantation.
Typically when a patient experiences Hepatorenal Syndrome as a result of cirrhosis a HIGH creatinine level is seen.
seen in erythropoietin-secreting tumors, in renal disorders such as hypernephroma and renal cysts, and in cancer of the liver". The fact you say liver and kidney function tests are completely normal I think would be encouraging signs that whatever is causing the high numbers is not affecting the numbers for those organs.
A year ago my sugar and insulin numbers where too high. My doctor prescribed metformin and told me my numbers should improve if I lost the weight (I was overweight at that time). I lost all the weight and I want to do the “glucose tolerance test” again to confirm or discard the possibility of having diabetes. At what time should I take the metformin the day before the test? How long does metformin stay in your body?? I do not want metformin to mask/change my glucose/insulin numbers.
I stopped metformin abruptly and started birth control around the same week I stopped the metformin, and so suddenly and intensely felt so much pain like I was dying. Its been 3 months and I haven't gotten better, I used to be so happy and hopefull now I feel completely hopeless, uneasy, and cannot enjoy anything. Will I ever get better??!!
thank you
s current kidney function and renal parenchyma of 8 mm, it would be a good decision to go for conservative surgery. Though there is a small chance that he may require Nephrectomy at a later stage, Pyeloplasty would be the best treatment at this stage. Nephrectomy is typically indicated when renal parenchyma is less than 3-4 mm. So if you understand and agree that there is a small possibility that your father may require a second surgery later, you can go for a pyeloplasty now.
I assume you likely already had since you had a kidney function test and whomever ordered that test knows the results. What kind of follow up are they giving you for this and what is the doctor's recommendation?
This page does reference vemlidy with regards to renal issues. https://www.rxlist.com/vemlidy-drug.htm.
Again, we urge you to come up with the appropriate course of action with your doctors and hope that others weigh in here on the forum. Best of health to you.
In patients with normal renal and hepatic function, the dosage of colchicine should be reduced when used with potent CYP450 3A4 inhibitors or within 14 days of using them. For the treatment of acute gout flares, the adjusted dosage recommended is 0.6 mg for one dose, followed by 0.3 mg one hour later. Administration should not be repeated for at least three days. For the prophylaxis of gout flares, the adjusted dosage should be 0.3 mg once a day if the original regimen was 0.
Chronic kidney disease is caused by diabetes mellitus, high blood pressure, polycystic kidney disease and some medications like pain killers. Medications are given to reduce the blood pressure and to correct the anemia. When the renal function is below the optimal level then dialysis is initiated. At the end stage of renal failure renal transplant from a competent donor would be the therapy of choice.
Hope this helped and do keep us posted.
When treatment is required, restored renal function allows use of combination therapy with IFN and ribavirin. Limitations of current HCV therapy include lack of tolerability and suboptimal response rates. New antiviral agents that can be used in dialysis patients (e.g., ribavirin alternatives) and in the posttransplantation setting (e.g., IFN alternatives) are needed to improve outcomes in these populations.
It is not unreasonable to take two 1000 mg Metformin tablets a day, provided you get regular liver function testing. Or three 500 mg tablets. But you should not do so blindly. And you can't count on "feeling" to sense your glucose levels.
Intense blood glucose testing is the only way to get a handle on whether or not your medications are being properly used. Many diabetic clinics have a download feature where you come in and they download information from your meter.
5 Kg (without taking METFORMIN)
Then when I went back to my old infertility specialist gynecologist , she told me she already knew all this and she also gave me a prescription of METFORMIN SR 500mg but Slow release metformin and she said good time to take this is afternoon instead of night. and only to take them for only 3 months and not more than that... She also said it is better I remove my fibriods thru laparoscopy. She told me to test for AMH by EIA and I did so , It was 2.
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