Metformin and kidney damage

Common Questions and Answers about Metformin and kidney damage


317787 tn?1473362051 I just have to be really careful. So far so good. I have read that the metformin can cause liver and kidney damage so was worried about it, especially since my liver is damaged. Then when I got so sick had so many side effects I got scared that I might be doing damage to my already damaged liver.
Avatar n tn I have been taking metformin for a week and have lost 19 pounds i am taking it for pcos and it has worked wonders i also have a normal cycle now i dont know if you have one or not but if you dont hopefully it will help
Avatar n tn Metformin has been known to cause kidney and liver problems, but this does not happen in all patients, and there is some evidence there is a co-factor, in development of damage, such as alcoholism, or a combination of other drugs. The national database PUBMED has the studies. All in all, the drug has a relatively good safety record. I would not fear taking Metformin if your physician recommends or concurs with your suggestion.
Avatar n tn I have taken Metformin 500 Mg x 2 times /day for nearly 3 years, but a year ago until now my feet are swollen, and I have bone spur on the left heel of my foot that is more growing bigger. This foot is in pain when I walk. Everyday when I take Metformin I usually have constipation and the top of my feet are swollen up. My fingers are so numb, and my urine is dark yellow and opaque.
Avatar f tn I try so hard to take care of myself and I know that my results point to only very mild kidney damage (if any), but I just cannot handle any more medical issues, and I have no idea what to expect or think. I wasn't sure which forum to post this in, but I thought I would give it a shot! Thank you!!
568322 tn?1370169040 The risk is from lactic acidosis if you have advanced liver disease and can't clear lactate, NOT from Metformin causing liver failure. Many diabetics have some kidney damage and liver disease (yes, diabetes is considered liver disease too and it can raise liver enzymes) and they use Metformin without going into liver failure. "I was told that injectable insulin is much safer for liver patients.
2157587 tn?1336732580 Metformin action in diabetes treatment is linked with metformin diet and metformin ingredients. Metformin reduce blood sugar levels, curing diabetes. Metformin ingredients work to reduce the amount of glucose produced by our livers and the amount of glucose absorbed through the stomach. Insulin is the harmone produced by the pancreas that reduces the glucose levels produced by our liver.
Avatar n tn I've been diagnosed with PCOS recently and will start Metformin and Clomid. I've heard the chances of having a healthy pregnancy with these meds are 40% for PCOS women which isn't too bad but wish it was more like 80% : ) Just wanted to hear any success stories to help cheer me up.
Avatar n tn 5 mg of enalipril daily, as it is believed to lower the risk of kidney damage evening this case. 3. It sounds like you have educated yourself on your disease (as we all must) enough to question your doctor. That is what you must do, and if you do not feel comfortable with any recommendation, seek another opinion and if necessary, find another endo.
990091 tn?1249200314 3 years ago I was diagnosed with PCOS, my Dr. prescribed 2000mg of Metformin/day, and Yasmin BCP to help regulate my sporadic menstrual cycles. I stopped taking the Metformin, due to insurance issues, and now I'm back on the 2000k/day regimen. Since my initial diagnosis of PCOS, I found that I had an ovarian tumor (teratoma), in addition to a sudden attack of hypothyroidism. In 2007 my TSH levels were 68.
Avatar f tn Tingling and numbness can be signs of nerve damage caused by uncontrolled and unmanaged diabetes - excess and unknown glucose levels. Does your husband have a home glucose test meter and is he testing his glucose levels at the appropriate times? More can said about this once we hear back from you. Also, not mentioned is his last A1c test result.
Avatar m tn ) and possibly the cause of my kidney damage. My insulin levels are normal (albeit high normal) but this condition can show up with normal labs. Who knew right?
Avatar n tn He feels that he should have taken him off the metformin as soon as his creatinine level reached that point and sent to a kidney doctor and because he didn't do that my husband has now suffered permanent kidney damage. What are your thoughts on this and do you think that his creatinine level will come down any more? Thank you! This discussion is related to <a href=''>High Creatinine Levels & Kidney Transplant</a>.
545538 tn?1295995617 The study did find significant risks linked to obesity, including a higher risk of death from heart disease, diabetes and kidney disease, and several cancers that have been linked with obesity, such as breast, colon and pancreatic cancer.
Avatar f tn im feeling less numb and more pain. and pain is a good thing. pain means no nerve damage. I haven't had that tickle and itchy feeling in about 3 days and the teeth pushing together thing in about 4 days. my lip hurts like its chapped and burning, but im happy about that. i know i still have at least 2 or 3 more weeks, possibly more before im 100% healed. its just a matter of waiting and being patient. hope you all have a speedy recovery.
Avatar n tn My question now is that my doctor refused to give me a post-methotrexane lab work to test for the liver and kidney as the methotrexane could cause of some damages to them. She said she does not do that unless you have a history of liver or kidney's problem. I don't know what the signs and symptoms of liver and/or kidney's problem are so how would like able to tell whether or not I should be worried?
Avatar n tn About six months ago I finally got over denial (hard thing to achieve) and started medical treatment, Metformin and Lantus, I experienced relief in many of my symptoms but I´ve developed neuropathic pain, hell of a curse it affects my life in all the ways. I can hardly think or work. I am taking carbamazepin, gabapentin and vitamin B to fight this but the pain is incredible mostly from my abdomen down.
Avatar f tn I have been having lots of problems.. kidney failure, liver disease, and pins and needles, shooting pain etc.. I have been put on Vit D 3 times now at 50,000 iu a week for 9 weeks as my level was 9.. now I have been sent to the Cleveland Clinic and found out I am pre-diabetic but with all the complications of a full blown diabetic.. I am now in a wheelchair and they said I have neuropathy and that all my probs are a combination..
Avatar n tn Statins, and I also believe, Metformin causes muscle and tendon damage. Actually, it's more that it depletes your body from collagen and prevents it from healing from everyday normal use. CoQ10 and collagen are super important for anyone on statins.
1500387 tn?1460743620 In another study, 11 teenage girls with PCOS were given Metformin and a high-protein, low-carbohydrate diet and 10 of them resumed normal menses. Metformin Increases Fertility in Women with PCOS Metformin increases fertility in women with insulin resistance and/or PCOS. PCOS is known to prevent ovulation and conception. Women with PCOS who do conceive often suffer from miscarriages within the first three months of pregnancy.
558301 tn?1215734456 I understand that high blood sugar levels are associated with higher risk for infections and complications and that Metformin is sometimes associated with lactic acidosis when taken just before/after surgery. My concerns: - is it safe for my mother (75yrs) to take MetforminHCL the day before and day after surgery? - What can I do to help if/when her blood sugar goes too high? - When (at what blood count) does it an emergency?
Avatar n tn My HA1C is 68, no retinal changes, overweight, mild high blood pressure. Take Metformin and Amlodipine. Went to dr. about 3 weeks ago; everything fine except I complained of right side pain from under my arm to bottom of rib cage that sometimes radiates to under right shoulder blade. Dr. blew me off - said to go to a physical therapist. Today I get a call from nurse saying there were very slightly elevated levels of protein in my urine and that I need to start medicine (bevacor?
Avatar n tn The foul, sulfuric rotten egg/bad red wine burps and flatulence (and diarrhea) are mortifying. I have studied the entire human body (in my profession), and have close friendships with several internists. However, I have no health insurance. Based on what I've studied and have been told, the most likely culprits are gastroparesis (very slow emptying of the stomach) OR gall bladder disease.
Avatar n tn Most burning feet treatments focus on preventing further nerve damage and reducing pain. Causes of Burning Feet Most often, neuropathy, or nerve damage, is the cause of burning feet. Damaged nerve fibers are more likely to become overactive and misfire. The damaged nerves send inappropriate pain signals to the brain, although there is no wound or injury. In most people with neuropathy, the leg nerves tend to become damaged first, at their furthest ends in the feet.
6214022 tn?1379615564 Having high sugar levels can cause all sorts of problems, from nerve damage, eye damage, kidney failure and amputations due to poor circulation. So it is very important that you take the medication as prescribed as eat sensibly. I was started on Metformin 500mg a week ago and I find I am fine. I take the medication after my evening meal as prescribed. I have been glucose intolerant for a number of years, but my last average reading went into the diabetic range.
Avatar n tn I am trying to figure out if I have cause for concern here, as the research I have done suggests that any eGFR below 59, for a woman, is suggestive of possible kidney damage, and an even bigger concern is when subsequent labs continue to show a drop, as they have in my case. I am obese (240 lbs), so I know that can affect the numbers, but I also have been plagued, over the yrs, with various auto-immune issues (ITP, Hashimoto's), and I know that that can also cause damage to kidneys.
Avatar n tn I am trying to figure out if I have cause for concern here, as the research I have done suggests that any eGFR below 59, for a woman, is suggestive of possible kidney damage, and an even bigger concern is when subsequent labs continue to show a drop, as they have in my case. I am obese (240 lbs), so I know that can affect the numbers, but I also have been plagued, over the yrs, with various auto-immune issues (ITP, Hashimoto's), and I know that that can also cause damage to kidneys.
Avatar f tn I'm glad Metformin is safe for you and working. I went to my dr and she said that Metformin can cause liver damage, but all medications have risks. I'm already on a statin so I'd like to limit the meds, if possible. I'm going to a diabetes management class so I hope to control this with diet and exercise. I've already started by limiting snacks at night. Fasting was 97, 2hrs. after lunch was 99.
Avatar f tn If you are a diabetic and on Metformin DO NOT get a contrast CT without talking to your doctor first because you will have to stop taking your Metformin before and after the CT so you don't risk kidney damage. They didn't tell us that either. Luckily I learned about it before something bad happened. Curious to see how it all turns out on Monday!
Avatar n tn I think everything is over and I clean up. I walk out of the toilet and in about 2 minutes time the stomach cramp and the fainting sensation comes back (I've fainted only once to date from this and was out for about 15-20 minutes). 6. When I get back to the toilet I have a really violent Diarrhoea episode in pure liquid state.