Hey Jenn...I was keeping rx's of both Macrobid (I, too, found it worked best, infection or not) and Pyridium (specific for bladder pain, and is now an otc med) on hand because I 'thought' I was getting frequent UTI's. However, most of the time when I went to Urgent Care, the urinalysis came back 'negative'. Sometimes it was 'positive', but rarely.