My Dr and I discussed putting me on Lyrica (which I was on a few years ago, but stopped taking, don't recall why) and I called my pharmacist because she told me about the huge side effect of weight gain with Lyrica, it's almost guaranteed, and my pharmacist told me that Lyrica is a dirivative of Neurontin, which has a much lower incidence of weight gain, and they are nearly the same medications. I then decided to go on Neurontin instead.