Nocturnal cramps can be associated with pregnancy, obesity, smoking, iron deficiency and anemia, nerve disease, polyneuropathy (which can be associated with hypothyroidism, heavy metal toxicity, toxins, and many other conditions), other hormone disease, such as diabetes, and kidney failure (which can be associated with vitamin and mineral deficiency
Some drugs and medications have been associated with
restless leg syndrome including caffeine, alcohol, H2-histamine blockers and certain antidepr