I'm posting this for my husband (40, 277, in good physical condition previously, with physically demanding job), who has been having medical issues for a year now. It began with waking up in the morning with pressure in his lower back that was remedied by going to the bathroom. Bending, twisting, picking up things, etc. never bothered him, which seemed to indicate it's not a back problem. Then it moved on to constipation, & when he could go his stool was flattened.