I lost my gall bladder in 2008 for unknown reasons, diagnosed with fibromyalgia 6 months after surgery, messed up my cycle pretty bad - thought I was going into early menopause, developed reactive
hypoglycemia, pain in my extremities like a diabetic neuropathy, constant abdominal pain, and inflammation of the thyroid. My Endocrinologist told me that the body pain and extremity pain should subside while on the metformin. She put me on 500 mg. once daily and it has helped.