After a few years on combination narcotic analgesics, (acet w/
hydrocodone, etc,) I eliminated the tylonol all together,
and now use oxycodone IR 15 mg. When we have multiple issues, they all interact. I've been fortunate to find pain relief through pain managment doctor, whom I've informed of my health concerns, and agreed to treat me with out tylenol, nsaids, etc...just the oxycodone. It does help manage all the other stuff too. It makes no sense being miserable day to day.