How phenytoin works
Common Questions and Answers about How phenytoin works
dilantin
In a small study, phenytoin-induced seizures occurred most often in patients with serum phenytoin concentrations of 50 mcg/ml or higher.[393] Peripheral neuropathy, usually occurring weeks to months after drug initiation, has also been reported in patients receiving phenytoin. A single case report describes the onset of neuropathy within a few hours of drug administration.[9780]
Adverse GI effects of phenytoin therapy include nausea/vomiting, constipation, abdominal pain, and anorexia.
Folic acid supplementation in folate-deficient patients with epilepsy changes the pharmacokinetics of phenytoin, usually leading to lower serum phenytoin concentrations and possible seizure breakthrough..."
It however says that initiation of Folic acid and phenytoin together is beneficial.
Since you can't go back and start all over again, you can take a small dose. It has been observed that as los as 1mg dose can perturb phenytoin’s levels, You may take doses lower than 1mg/day.
Moban® brand of molindone hydrochloride contains calcium ions which interfere with the absorption of phenytoin. Ingestion times of phenytoin and antacid preparations containing calcium should be staggered in patients with low serum phenytoin levels to prevent absorption problems”. Taken from http://www.rxlist.com/cgi/generic/phenyt_od.htm
Our population is divided into 4 type of metabolizers ranging from rapid to slow metabolizers depending upon the speed of elimination of drug from body.
Thank you for your question, you are relatively fine with Phenytoin and the seizure episodes in a form of lack of speech are the residue of a generalized type seizure. I don’t have a full description of your consciousness during the lack of speech episodes to decide whether this start is a partial epilepsy which can continue in a generalized or it is a generalized one from the first moment..
Hello AB, welcome to the medhelp forum. Phenytoin can cause certain side effects like dizziness and mental confusion. Some people may also manifest incoordinate movements. Weight gain is not a documented side effect. It could be related to your alcohol consumption or wrong dietary habits and lack of exercise. An occasional one or two drink may be fine but moderate or large amount can cause significant increases in blood levels of phenytoin due to induction of hepatic enzymes.
Encorate-300mg one tablet, Eptoin(phenytoin)-100mg one tablet , Himalayan company's liv 52- one tablet
night: Encorate-500mg one tablet, Eptoin-100mg one tablet l, liv 52 two tablets.
YET HE IS GETTING PARTIAL COMPLEX SEIZURES EVERY THREE DAYS
Please help.
At first, he had trigeminal neuralgia and he was on carbamezapine 150mg twice daily and then 300mg twice daily. I just need to know how long he has to be on Citilin. Is it a safe drug to be used for long time? He also has hypertension and slightly high cholesterol for which he is on Norvasc 5mg & Atenolol 50mg and Atorvastatin 10mg and he is alo on Aspirin 75mg. He also has blood creatinine. Please let me know if he is on right drugs and right dosage?
I have taken brand name dilantin most of my life. I was always afraid of switching to the generic but finally decided to try it a few months back. Sure enough, I had a full fledged grand mal for the first time in 18 years. My blood levels showed I was low (well below the desired 10 to 20). Can anyone tell me why the generic works different than the brand name? I've heard they use different bonding agents for the capsules as one possibility.
Phenytoin (Dilantin et al) works best with me. It's off patent and about 70 years on the market. Low doses best. These repetitive thoughts are a brain electrical problem (inappropriate electrical activity), and while not as intense a problem as epilepsy, they can be treated the same way.
I take 50 - 100 mg as a dose and it smoothes those intrusions and does NOT make me tired or have noticeable side effects except feeling normal.
The one thing that sticks in my mind is that my EP told me nothing, is going to stop the PVC's. I find that less is more, sometimes I have to let them really get ripping then I take the medicine and it works better than trying to eliminate them. My med doesn't get rid of them it just takes the edge off. I don't know anything about herbs, but that alot of stuff your taking. Heal the lymes first. Your system needs less things to deal with not more.
During those times I had not yet been diagnosed and was able to go back to life like normal, however after the diagnosis and being on phenytoin and switching to oxcarbazepine i am feeling awful. Dizzy, nauseated, moody, extremely tired, severe headaches that come and go. All i get from my Neurologist is these are side effects that will eventually go away. Because i never know when these symptoms will come on too strong I have missed a lot of days at work during my probation period.
drugs like gabapentin, phenytoin are used for hemifacial spasm. Other options are botulinum injections and microvascular decompression surgery. Hope this helps. Take care.
I'm only 29 yrs. old and have been taking Dilantin since I was 15yr. old. My seizures have been under control the only time I actually had full blown seizures is when I was a teenager and I missed doses I had one and When my doctor decided to take me off my dilantin gradually since I hadn't had a seizure for 6 yrs. but, when I got completely off the medicine I had a full blown seizure from it.
told me to go back to the 200mg and she would have to talk to my Neurologist, I just had blood work done again and my phenytoin level come back at 2. How is that possible? I take my pills regular, I have had no seizures. I have such a hard time getting a hold of the Neurologist I thought maybe you could help me. Could my others pills be interfering. I have been diagnosed with Hypothyroidism since the seizure and high colestoral. I take Levothyroxine, lipitor, vitamin D, and calcium.
Addition of other antiepileptic drugs like phenytoin,lamotrigene and sedatives will be helpful for controll of his night symptoms.
it's been said that someone with epilepsy should not take a generic medication how true is this
Acute alcohol consumption increases the availability of phenytoin (Dilantin) and the risk of drug-related side effects. Chronic drinking may decrease phenytoin availability, significantly reducing the patient's protection against epileptic seizures, even during a period of abstinence. Any form of alcohol, even beer is contraindicated for some time when you are weaned off dilantin.
Sexual activity is an exertional activity which can cause exertional or sexual headache.
A few weeks ago I woke up with yellow crust on the corner of my lips and it went away in 2 days, and today I woke up and it's in the exact same spot again except a little more then before. It doesn't hurt or itch, it feels like my lips are very very dry. I don't smoke, I have grandmal seizures and my medication is phenytoin and kepra but I didn't read anywhere that would be a side effect so I'm worried this could be a STD or something.
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