The fluticasone component of
Advair is a steroid, and steroids, since they affect cellular machinery, do NOT
work instantly. My husband is a professor of physiology, and he tells his students that it's a matter of hours to days to get the steroid effect which calms the irritated bronchi. If you're basically healthy, the inhaled steroids should cause you no problem unless your asthma is so severe that you require steroids daily and frequently over a period of years.