Hi, I'm definitely going thru perimenopause and even though I'm on Bio Identical Hormone Therapy, I still suffer every month. It seems like nothing ever just goes smoothly. I also have panic attacks. I also think I suffer from mild depression. Even though my panic attacks have subsided greatly in the past few month. (I have been on the hormone therapy for a year now.) I still feel uptight, edgy, moody, no interest in sex, the list goes on and on - all the time.