Hiv cure trials

Common Questions and Answers about Hiv cure trials


163305 tn?1333672171 Finally it seems like there is research to find a cure w/o that nasty interferon. Does anyone know about this and possibly have any information? First Candidate from SCYNEXIS Novel Cyclophilin Inhibitor Platform, SCY-635, Establishes Proof of Concept in HCV-Infected Adults Research Triangle Park, NC -- January 8, 2009 -- Drug discovery company, SCYNEXIS, Inc.
5295565 tn?1366124433 i've never tried to cure this because of a allergy to interferon;at the moment in italy there are only 2 hospitals where you can ask for interferon- free but it's very hard to enter is the situation in yours country?? thank you and forgive my awful english.
475555 tn?1469307939 I am 64, in good overall health, recently diagnosed with HCV, genotype 1b, still have pretty good blood markers, and am probably a good patient for drug trials. I know about the NIH trials website, but it isn't patient-friendly and takes a whole lot of time and trouble going through it and then trying to contact the people doing the trial, maybe for nothing. With hundreds of trials going on, I could spend the next year looking for one.
Avatar n tn My mother insisted that I do not receive donor blood (at that time HIV was a big scare); however, the nurse at the hospital ensured her I would be safe. Basically, the blood transfusion that saved my life when I was born is now slowly killing me. I am trying to deal with this disease the best I can. I just want my life back. I feel so dirty and ashamed to tell people the real reason I am sick. I know how people will look at it; I remember how I viewed it the moment I found out.
137025 tn?1217768341 Vertex is also planning trials for BID dosing (twice a day), co-infected (HIV-HCV), and harder to treat groups (that could be Afro-Americans or advanced Liver disease groups). Even if the news were not as successful at the EASL the planned trials for the easier to treat genotypes will be able to be constructed with much more precision based on the data gathered from the Prove 1 and 2 trials. That could result in taking a lot of "trial and error" out of the trials. Sorry....
Avatar f tn With the recent approval of new drugs on the market, more and more people being diagnosed, a multitude of trials to select from for those who opt out of traditional care with its severe side effects, and the need to share information about treatment experiences with drugs approved for investigational use only, etc, etc, it could really fill a gap in helping people access care. It appears that there are a few of us who are interested. I will ask that they express their opinion here.
Avatar n tn In September I posted that my husband would start the Tarvacin trials this month. Actually, he was supposed to receive his med administration this past Monday. We went to his evaluation visit on 10/31. Unfortunately, some prior blood work indicated an elevated AFP (alpha feto protein), and he had a CT scan. The scan indicated a significant number of enlarged lymph nodes along his gastric vein. Under the Peregrin guidelines, he was disqualified until we could identify the problem.
Avatar f tn Targeted conditions include Dengue Hemorrhagic Fever (DHF), HIV/AIDS, and Hepatitis-C (HCV). At present, regulatory barriers specific to the Hemopurifier® do not exist in India. As a result, the opportunity for Aethlon to commercialize its technology within the country will be based on obtaining clinical data sufficient to drive practitioner acceptance in the marketplace.
Avatar n tn Potential cure for HIV discovered 06.28.07, 4:07 PM ET CHICAGO (Thomson Financial) - In a breakthrough that could potentially lead to a cure for HIV infection, scientists have discovered a way to remove the virus from infected cells, a study released today said. The scientists engineered an enzyme which attacks the DNA of the HIV virus and cuts it out of the infected cell, according to the study published in Science magazine.
1815939 tn?1377995399 High Rate of Viral Clearance, No Injections Two phase 2, open-label studies evaluating the safety and efficacy of all-oral combination therapies for patients infected with hepatitis C virus (HCV) have shown that high rates of sustained virologic response (SVR) are possible even in the absence of interferon. Results from both studies were published in the January 16 issue of the New England Journal of Medicine.
Avatar m tn Partners and collaborators include the University of Pennsylvania, Merck, ChronTech, National Cancer Institute, U.S. Military HIV Research Program, NIH, HIV Vaccines Trial Network, University of Southampton, US Dept. of Homeland Security and PATH Malaria Vaccine Initiative. More information is available at
Avatar n tn One thing you might want to remember is that to get in these trials requires a bx. And in these early trials they exclude anyone with cirrhosis. Not saying you have it but if i was you i would do the fibrosure test soon. At least for a guideline on where you might stand damage wise. Just my thoughts, best to you.
264121 tn?1313033056 However, I recently came into contact with a girl from Romark whose mother has Hep C. Romark is trials both with Alinia in conjunction with interferon alone, as a monotherapy by itself, and as an adjunct to the the combo therapy. Alinia is an already on the books drug FDA approved for treatment of giardia, which I believe is a parasitic intestinal disorder. Which means that until the FDA approves it. treatment of Hep C outside the studies would, I suppose, be off-label.
107513 tn?1232290064 There is no placebo arm in the PROVE 1 trials, (those are the Phase 2 trials for treatment-naive patients in US) Group A will receive Pegasys, Copegus and placebo for 12 weeks. This group will be considered the control group (treatment that your doctor would give you if you did not take part in this study.) The word "placebo" in this statement is what may be throwing us off.
Avatar n tn Has any one heard of it??.... It is in the second phase of clinical trials. It sounds very promising but who knows???
Avatar m tn A lot of the naps we use for hepatitis b was developed for hiv as the naps block the virus from multiplying. I notice in the HIV community they are always leaning for a functional cure where the hiv virus is still in the body but no longer able to effect the person. For hep b, will we lean toward a functional cure also ? Since most of the funding and research for hbv originated from hiv research, will we lose research and capital if hbv is not heading in the same direction.
Avatar n tn Have been doing a lot of research on natural products, so why aren't there clinical trials for that? I have ready several time that frozen thymus has an excellent cure rate, some people are cured with collidal silver. So why aren't we doing clinical trials on these cures?
Avatar f tn I've been googling like crazy about cures, i do not wish to seek temporary treatment, i need a cure. I want this out of my life. I am very interested in DRACO, it seems believeable. What I do not understand about herpes is: How does herpes survive in the body?. What is keeping it alive?. Why is it that people know where it hides dormant but there is no way to directly attack the virus?. Why can't or is it even possible for our own bodies/immune system to find && destroy the virus?
Avatar m tn As we know hcv cure, Solvadi is a drug which failed for hiv first. Amount of money invested in hiv market is huge if you compare it to the money spend on other diseases.
Avatar m tn Recent trials on animals have shown it is between 85 and 100 per cent effective at blocking HIV and Herpes transmission. 4. Astellas ASP-2151 The most promising of the long-awaited Helicase Primase Inhibitors (HPI) drugs. And I really mean long-awaited. This is like super-acyclovir, and there's been some speculation that it could inhibit the virus so effectively that asymptomatic shedding may not be an issue. 5.
Avatar n tn just check our latest posts the only cure is mking hbvdna undetactable by tenofovir for 1-3 years and then peginterferon add on for another 2 years hbsag quantification in iu/ml by abbott architect is needed to monitor this therapy and predict hbv clearance.
Avatar m tn Two grants from the National Institutes of Health will allow Saint Louis University researchers to build on breakthroughs in understanding the hepatitis B virus and begin the search for a drug to cure – not just halt – the illness. Last year, John Tavis, PhD, professor of molecular microbiology and immunology at SLU published research demonstrating a way to measure and then block a previously unstudied enzyme, RNAseH, to stop the virus from replicating.
206807 tn?1331939784 As in the case of cancer and HIV more $ is going to find better treatments then finding a cure. But even a cure for those 2 are very daunting tasks that fail time and time again due to many factors. Overall I don't think we have much to worry about as our heath care system is better then in Liberia, as why you see the mass amounts of death.
Avatar m tn SVR (cure rate) WITHOUT Hepatologist: 66% (genotype 1 and 4) SVR (cure rate) WITH Hepatologist: 34% (genotype 1 and 4) SVR without Hepatologist (signficant liver damage): 25% SVR with Hepatologist: 69% -------------------------------------------------------------------------------- While the incredible difference in SVR rates is more than anyone would have guessed -- from what I've seen posted here over the past two years it doesn't surprise me that treatment outcomes would be signficantly
Avatar m tn More evidence that Big Pharma is believing the time has come to cure HBV comes in the form of patent application WO 2011/047312 by GlaxoSmithKline (GSK). Indeed, the intended mechanism of action of GSK’s curative concept is the same as for ARC520 by Arrowhead Research: knockdown of the viral transcripts, particularly HBsAg and HBeAg.
253566 tn?1219683299 I am not keen to encourage people with non-specific or multiple symptoms to automaticaly blame them on treatment. The heading of the post was 'Cure' Disabled Me! The content of the post did not necessarily validate that very specific claim.
Avatar m tn ) Most of you folks continue to do slow clinical trials just on ETV, or Tenofovir when there are other more effective therapy options available? Why do the drug and insurance companies tell you what to do and what to give us, and how to treat us, and with what? Everyone is talking about fixing health care in America - make it about helping people not about making money as the main goal. And it is just about time to do something. Especially with the virus such as this, that can be treated.
Avatar m tn I'm at a the stage with my Hcv to need treatment or so my docs are telling me. I'm HIV 27years and Hcv 20 years my T cells are 200 not a great number , and I'm A1genotype Hcv . I just found out I'm cirrohtic and just wondered if any one had any advice for me , my fibroscan was 30.3 so pretty bad reading .
Avatar m tn Jerusalem, Sep 5 – In a major breakthrough, Israeli scientists have developed a method that can wipe out HIV infected cells without affecting the healthy ones but it will be a while before it is available to the public, a medical journal says. Although the researchers have registered an Israeli patent, the treatment must still go through trials on animals and humans, the latest edition of the British journal AIDS Research and Therapy says.
Avatar n tn I am looking to see if anyone with HIV has tried Monavie. Would like to know if your bloodwork improved, energy levels increased or did you stay unchanged. This is a really good natural juice that provides excellent nutrition and its high in antioxidants. your input would be greatly appreciated. friend in need.