Hiv cure breakthrough 2010

Common Questions and Answers about Hiv cure breakthrough 2010


1711722 tn?1356491154 Yes, first thing is do no harm, so you can come back and fight another day IF this is a viral breakthrough. Maybe all is not lost? So breakthrough was after 8 weeks of Victrelis? I'm I right? I would continue treatment if possible and see if your next viral load test still shows an increase in viral load or not. If you are having a breakthrough is will rise up fast. Maybe you can get another VL test before waiting a month? maybe from your primary doctor?
585414 tn?1288944902 A cure for the common cold may finally be achieved as a result of a remarkable discovery in a Cambridge laboratory By Steve Connor, Science Editor Tuesday, 2 November 2010 In a dramatic breakthrough that could affect millions of lives, scientists have been able to show for the first time that the body's immune defences can destroy the common cold virus after it has actually invaded the inner sanctum of a human cell, a feat that was believed until now to be impossible.
Avatar m tn // ONLY 170 people got HIV from 10,000 with HIV +. What happen, the HIV sleeping? why only 1.7% infected? When the HIV into in blood why not 100% infected? (without PEP).
220090 tn?1379170787 This is the reason it is possible to cure HCV with a PI, but HIV and HBV are not curable with PIs. The current PIs attack the Ns3 protease within the RNA and since they are very selective, the can't inhibit reproduction of all mutations of the virus; thus, SOC is required along with the PI. The newer PIs in early stages, attack a broader range and the polymerase inhibitors take an entirely different approach.
163305 tn?1333672171 Awesome, but does this mean she will now be hiv positive I wonder? I guess if faced with immenent death or hiv, I would opt for hiv.
979080 tn?1323437239 We are all, all for something to make the cure rates better and the times shorter (or even just the cure rates better honestly) for all genos!
87972 tn?1322664839 the HCV community lacks the cohesive nature that drove research and funding during the HIV crisis. Interestingly enough, the bulk of HIV/HCV coinfected patients that share their stories in here lately tend to be more frightened about the HCV aspects; many of them consider HIV the lesser problem, and have their HIV well controlled. At what point will you initiate IFN into your diet; and will you also include NTZ eventually as well?
2135877 tn?1381864726 I had a viral breakthrough at my four week test. What do I do now? What do I do with all these extra drugs I have? What trials should I research? I was treatment naive and I'm genotype 1A. Thanks, guys. I appreciate all you've done for me. Here are my test results: Component Hepatitis C RNA Quant Standard Range 2/22/2012 7075261 A 4/20/2012 90 A 4/27/2012 139 A 5/10/2012 1986 A Component Standard Range 2/22/2012 4/20/2012 4/27/2012 5/10/2012 WBC 4.0-10.0 1000/mm3 5.0 5.1 4.4 2.
Avatar m tn my impatience must be showing. 2010 is such a long time to wait for telaprevir, but that is what my doc wants me to do. I have this very smart gut and it tells me that telaprevir WILL be approved, it's just so hard waiting. My liver doesn't like it much either. Do I need to be on the lookout for the escaped varient? I'm pretty good with a broom when it comes to shoosing away the possum in the cat food, bet I could get after that varient. I'll let you know.
Avatar f tn Impact of Hypothetical Treatment Slowing Progression A treatment breakthrough that slowed disease progression – much as we have managed to do with HIV/AIDS and several cancers – would result in far fewer people with Alzheimer’s disease in 2050 in the severe stage when care demands and costs are greatest. Assuming the breakthrough occurred in 2015: •In 2020, the number of people age 65 and older with Alzheimer’s disease in the severe stage would drop from 2.4 million to 1.1 million.
Avatar m tn Bille, So sorry to hear you relapsed. It's got to be difficult after you get so many positive signs throughout treatment and put so much of your heart and soul into treating. But there will be others who relapse, and the drug companies are looking to dominate the market, so there will be a "cure" that fits all, just like there is for HIV. Greed is good, at least in this example.
Avatar m tn It seems from what your saying blocking would be better than inhibition for the purpose of Immune Response. Arrowhead didn't mention or show any effect on immune recovery which is very important for the overall goal of the therapy. I hope Replicor continues to make progress, since they have even presented results on immune reocvery. 1.
Avatar m tn Can you and I wait for the final release of VX-950, which is purported to be 2010? I'm stage 3-4, beginning Cirrhosis. This is the question the doctor is best able to answer according to timely bloodwork. Let me know how you react to the treatment, and best of luck in clearing...
Avatar f tn NYCMark - finished, waiting for 3 months post PCR (detected with low viralAcute hiv infection Common cold Croup Hepatitis a Pharyngitis - viral Viral arthritis Viral lesion culture Viral pneumonia load, will retest) Randalee - Feb 07 Valtod - 8/27/07 Proactive - finished 72 weeks of tx (3/12/08) with high dose riba (1600 mg-20mg/kg) Bill 1954- 2nd Tx; finished 96 weeks of treatment on 7/18/08 with 200mc PEG-Intron and 2000mg/day riba.
Avatar n tn Entry inhibitors like REP9 AC and Myrcludex-B are promising as they are the only drugs that offer a complete CURE for Hepatitis B compared to immune modulators like Pegasys and Anti-virals like Entecavir... I think more research and concentration should be diverted to release inhibitor drugs as they seem to be promising and appropriate....
Avatar m tn Obviously adjuncts have so far proved incapable of cure, but which of you who have not been able to REACH a cure using SOC would not gladly trade a viral load of 2 million for 10 thousand?? It's not JUST about inflammation, although that's somewhat true, but the virus also changes the way we metabolize, the whole lipid process is thrown off, as is the whole endocrine process, and God only knows what else.
29837 tn?1414538248 While he couldn't give me a definite time line for the compassionate release, he did say that telepravir being in Phase III, they are seeking approval by the FDA in the second half of 2010, and making it available through prescription instead of the current clinical trials. Interestingly, he added a comment that we could hopefully expedite the "compassionate" use approval by the FDA if we write them an email stating the urgency for those who need this NOW.
Avatar m tn Only the transplant center will know your overall health at this point and they will recommend the best treatment for you considering your physical health. Yes, SVR (cure) rates post-transplant are dismal. About 33% using peg-IFN and RBV. There will be a clinical trial at Mayo Clinic Rochester, Minnesota, coming up that will be for post transplant patients.
144210 tn?1273092382 Alinia has not been shown to be superior to placebo for the treatment of diarrhea caused by Cryptosporidium parvum in HIV-infected or immunodeficient patients. The most common adverse events reported by patients receiving Alinia have been abdominal pain, diarrhea, headache, and nausea. In controlled trials, the frequency of these events has been similar to patients receiving a placebo.
Avatar f tn The extent of the PI resistance you built up will depend on how long you took the Inci - at what week did you stop and at what week did tests show breakthrough? My point about quad above was only that the wait will likely be shorter than for all-pill solutions, not about a trial. In fact, it's surprising the current trial enrolled you given the previous PI exposure. All you need for quad therapy is approval of one non-protease drug.
Avatar m tn Launch no-go for eco (engine cut off) sensor, keeps main engines from running dry and a bad day! There has to be a launch every 2.5 months (average) with the windows to finish 2010! Schedule is tight! Hope next years hurricane season is just like this one for us! Happy Holidays and Merry Christmas to everyone! All the best back at you jmjm!
Avatar f tn 1998-99 12 mos peg interferon with ribavarin responded, had a breakthrough(elevated LFTs and was almost listed for a transplant when they dropped back down?), then back to non-detected. First blood test relapsed. 2012 interferon, ribavarin and incivek. I never made it past 3 weeks! I had a horrific reaction to interferon & ribavarin and had to stop treatment. I developed nerve damage, brain fog and have NEVER been the same.
Avatar f tn True that some treatment-naive people have resistant mutations or resistant virons from the start. Referring again to HIV, they've found recently that about 9% of those newly diagnosed with HIV already show resistance to some of the HIV treatment drugs.
Avatar f tn October, 2009 – 285,000 (start) December, 2009 – 231,000 (week 4) Jan, Feb – around 200,000 (week 8) March, 2010 – 150,000 (week 12) April, 2010 – 40,000 (week 16) May, 2010 – 4,000 (week 20) June – 500 (week 24) July - 700 (week 28) His doctor said that if his viral count went up at all, she would stop the treatment. So, she just informed us that she is stopping. We are, however, allowed to use up the 3 week supply we have left.
Avatar m tn Under ideal conditions, such as low level of HBsAg, this treatment offers a chance of a cure, it can also lead to your Hepatitis coming under control if you are a responder. Whether you can wait depend on many factors and must be balanced against the benefits of treatment.
Avatar n tn The issue that you discuss above, re-activation of the virus after achieving SVR, is a controversial subject that has not received sufficient long term study, other than statistical studies of SVR's, which show that about 98% of SVR's remain virus free over five to ten years. There are also a small number of those who 'relapse' after one or two years, after having been SVR, (the two percent above) and this is where the controversy becomes very cloudy.
29837 tn?1414538248 So why go through all this to possibly relapse? He thinks not. Who knows, by late 2010, there could be something even more powerful than VX-950 and for treating a relapse situation as well. He also mentioned that it will be at least six years before there’s a treatment without Interferon and the nasty Ribavirin. Can you wait? To his3707 As to your question of how do you go about getting the "compassionate use" of Telaprivir before its release?
Avatar f tn The only results I have seen is 100% (SVR 4) cure on nulls after a 12 week treatment. It is entirely possible that just the 2 antivirals alone (w/o RBV) would offer close to the same SVR rate. I believe that it is possible that a full 24 weeks might be required for the worst of the worst, or even adding one more compound, but my guess is that the trial above (and all 4 arms) will cure the vast majority of nulls. In my case..... since I am a naive.....