It is a rare syndrome in which arterioles of the skin dilate periodically. It results in a
burning pain and makes the skin feel hot. The specific cause of the syndrome is unknown. It may be caused by the use of some drugs, such as antihypertensives. It may be associated with certain blood disorders, high blood pressure, venous insufficiency, neuropathy, diabetes mellitus, systemic lupus erythematosus (lupus), rheumatoid arthritis, gout, spinal cord disorders, or multiple sclerosis.