Fentanyl and histamine release

Common Questions and Answers about Fentanyl and histamine release


Avatar f tn Skin conditions like psoriasis,dermatitis,lice,scabies and hives, internal diseases like liver and kidney disorders,diabetes, iron deficiency anemia, irritation and allergic reactions to chemicals,wool,soaps,cosmetics and certain foods can cause itchy skin. You can apply an anti-itch cream or lotion to the affected area. Oral antihistamine, such as Benadryl can also be used. You should take a comfortably cool bath and wear smooth-textured cotton clothing.
Avatar m tn Certain factors can trigger the release of histamine and the other chemicals from mast cells and this includes drugs (especially aspirin and other non-steroidal anti-inflammatory drugs, codeine and morphine, and some anaesthetics), alcohol, emotional stress, physical stimuli (heat, exercise and friction), bacterial toxins and insect venom. Liposuction is a physical stimulus and can trigger histamine release.
Avatar f tn Hydromorphone and fentanyl appear to be the least affected by renal dysfunction, and fentanyl has less hemodynamic disturbance (due to lack of histamine release associated with other opioids).39" "NSAIDs and opioids may be used at reduced doses in patients with chronic liver disease without cirrhosis. Patients with cirrhosis have fewer analgesic options.
Avatar m tn On yahoo answers...... (sounds good) "You've got lots of good advice here and I just had to add mine because I suffer from hives-- diagnosed as 'ideopathic urticara'- for months at a time. The best advice my dermatologist ever gave me: Don't scratch. When you scratch your cells burst and release histamines... you may find yourself swollen. I have had this condition to the point of being disfigured and in the ER being pumped full of steroids.
Avatar n tn Some opiates cause histamine release-- particularly morphine-- that can cause itching and a rash. Some high-potency synthetic opiates--namely fentanyl and sufentanil-- cause facial itching, particularly around and inside the nose. Some medications can cause a feeling of extreme restless called 'akathesia' that sometimes presents as intense itchiness over the body, especially the legs.
Avatar n tn After histamine the chemical involved in allergy is released it causes whealing,release of other mediators which open the blood vessels.The first rash is to do with histamine,the second- line is the blood vessels- pain due to leukotrines release.
Avatar m tn Quercetin inhibits the production and release of histamine and other allergic/inflammatory substances. Histamine is a substance that is responsible for the allergic symptoms in the body. It can be taken in natural form by consuming apples and red onions and is also available as a dietary supplement. You may discuss this with your healthcare provider for dosage and other instructions.
Avatar n tn I was on the fentanyl patch many years ago, but for several years, and at a high dose. After developing diabetes, my body temperature made the medicine enter my body too quickly and so created problems. At that time, there wasn't the option of oral - only IV. The only question I'd have is that the GI tract absorbs medicines in oral liquid form quite quickly - unless in a time release form - thereby reducing the slow release quality of the patch.
Avatar n tn I have been on Fentanyl patches for about 6 months and it was prescribed to wean me off of Norco 10/325 2 pills 4 x day after a surgery. I got as high as 75 mcg patch of Fentanyl every 3 days and then I developed some kind of allergy. The Pain Dr. says the allergy is to the adhesive, not the fentanyl. I am now down to 37 mcg every 2 days because the patches itch like crazy. I wake up in the morning and my patches are scratched off(even withTagederm) and there is blood on my sheets. My Dr.
Avatar n tn Hives develop in response to an allergic reaction, by the release of histamine. The allergen can be medications, food, extremes of temperature, exercise and viral infections to name a few. Since you developed the outbreak along with joint pains and fever, it could be a response to an infection. So, therapy lies in resolving the infection and anti-histamines. If the present antihistamines are not very effective you can consult your doctor for long acting ones.
Avatar m tn When ever you are exposed to allergen there will be release of histamine, this is responsible for raised lesions on skin leading to itching. The order may differ from individuals to individuals. You need to identify such allergen and prevent further exposure. Oral anti histamines and low potency corticosteroids will help to reduce the symptoms. I suggest you to consult allergy specialist. Take care and regards.
1399363 tn?1462342610 i was reading information about histamine intolerance and vit b6 many says vitamin b6 will increase sao so reduce histamine but i read some that says vit b6 synthesis histamine. isnt that gonna increase histamine? also citrus food are high histamine but it says vit c will help? could someone gives some inputs?
Avatar m tn Whenever you are exposed to allergen there will be release of histamine, this is responsible for sneezing first and then followed by further release of histamine in the skin leading to itching, runny nose, watery eyes etc. The order may differ from individuals to individuals. You need to avoid contact with allergen to avoid further complications. Also treatment includes anti histaminic and glucocorticoids against prescription.
1264863 tn?1391118193 I am going into to see my dr and need to switch off the fentanyl. Is there any easy way way to do this and what would be a good option in place of it???? I place one 12mcg patch on every other day and one 25mcg patch. Main reason for stopping is weight gain which is drawing me into major deppression. Any advice is good advice.
Avatar m tn The mast cell tissue release Histamine which spread to the air by some ways which cause allergic phen—.And I think the mast cell tissue is highly related to brown adipose tissu.Brown adipose is distributed in scapula,shoulder,neck, perineumIt.So,you might feel burning and scratch frequently in these place.Generally,I thought the instinct of PATM caused by histamine is immune system problem.So lots of people also suffer from rheumatic arthritis when they grow old.
Avatar n tn The tricyclic antidepressant doxepin has also been found to be an effective blocker of histamine release. Finally, a medication called ketotifen, which keeps mast cells from releasing histamine, has also been used with success. ref:http://www.healthatoz.com/healthatoz/Atoz/common/standard/transform.jsp?requestURI=/healthatoz/Atoz/ency/physical_allergy.jsp ref:http://dermatology.about.com/cs/hives/a/coldurt.
Avatar n tn I have also copied this down and for more information we have a Dermatology forum on MH Triggers for Mast Cell Disease Physical stimuli: Exercise, heat, skin friction, hot baths, hot drinks, cold exposure (especially swimming), sunlight, emotional stress, spicy foods.
Avatar n tn Hi, Hives are caused by inflammation in the skin and can be triggered when certain cells in the body release histamine and other chemicals into your bloodstream and skin. This may be caused by allergic reactions to medications or foods or other allergens.Additional triggers include physical factors such as environmental factors ( heat, cold, sunlight, water, pressure on the skin, emotional stress and exercise). Preventing the triggers will help prevent the symptoms.
1279189 tn?1275244868 No, with fentanyl on board you will have no withdrawal symptoms from the vicodin. However, it takes two or three days for the fentanyl to reach a steady dosage in your bloodstream, so you may need to overlap with the vicodin a bit as your body gets used to the change. You will not get a "buzz" or as you put it, increased spike in energy from fentanyl that you experience with vicodin.
Avatar f tn - MS Contin (Extended Release Morphine), - Nucynta ER (ER Nucynta) - Ultram ER (ER Tramadol, brand) - Opana ER (Extended Release Oxymorphone) - OxyContin (Extended Release Oxycodone) - Exalgo (ER Dilaudid) - BuTrans Patch (ER Buprenephrine) - Fentanyl Patch (ER Fentanyl) MS Contin, Opana ER, and OxyContin are typically prescribed 2-3 times per day or every 8 to 12 hours. Exalgo is prescribed every 24 hours. The BuTrans patch last 7 days and the Fentanyl patch lasts 48-72 hours.
Avatar m tn Any narcotic should, if possible, be slowly tapered as physical withdrawal is quite unpleasant. I did a fast taper that was not supervised by my doctor and it was less than ideal. Fentanyl can be a bit harder than Percocet, Vicodin, etc. Drinking lots of water is essential as it is really easy to get dehydrated. You can taper from the Fentanyl down and then cross over to a different immediate release narcotic and then taper down from that. Are you taking anything else?
1635132 tn?1305063930 If your headache is associated with allergies, this medicine may greatly help stop histamine release. Talk to your doctor about this for proper management. Take care and best regards.
Avatar n tn Trauma may release an antigen that interacts with the membrane-bound immunoglobulin E of mast cells, which release inflammatory mediators, particularly histamine, into the tissues. This causes small blood vessels to leak, allowing fluid to accumulate in the skin It can be treated by antihistamines or cromoglicate and sometimes steroids, as they prevent the histamine from causing the reaction. As the underlying cause of dermographism is not known, it can last for many years without relief.
1264863 tn?1391118193 Most of us find that finding an effective slow release/long acting opiate is a trial and error process. My physician worked with me to find the opiate that my system tolerated best and that also controlled my pain. I am hopeful that your physician will do the same. It did require several tries with slow release meds to find which one was right for treating my pain. It was a bit frustrating due to my multiple allergies. MS Contin was not effective for me either.
Avatar m tn Indeed Morphine is known to trigger asthma in some ppl. Actually morphine can trigger an attack because of histamine release. Histamine is a potent bronchocontrictor thus has the potential to induce an asthma attack. There are multiple opiates that may be more effective and appropriate for you, especially given you have asthma. I am not a physician - and to suggest a specific medication for you would not be prudent.
Avatar m tn s are VERY mild this time around! I was really expecting to go to hell and back with this fentanyl withdrawal but so far it has been 10x easier than my oxy withdrawals I went through last year. Anyone have any theories why my w/d this time around has not been nearly as bad as last time? I have been dependent for about 4 months this time around, using mainly oxy/dilaudid/fentanyl but I havent had oxy in awhile mainly just fentanyl and dilaudid.