The extra fluid and sodium increases pressure in your blood vessels, causing edema
associated with kidney disease usually occurs in your legs and
around your eyes.
Kidney damage. Damage to the tiny blood vessels in your kidneys (glomeruli) that filter waste and excess water from your blood can result in nephrotic syndrome. One result of nephrotic syndrome is low levels of protein (albumin) in your blood, which can lead to fluid accumulation and edema.
Worst case scenarios.