Ezetimibe nice

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Avatar m tn also statins like simvastatin were reported to boost response a little but better not mix 2 statins, in a report researchers of ezetimibe effect on hbv and hcv suggested the use of ezetimibe with interferon but without simvastin ezetimibe dose is 10-20mg daily but human trials with dose 50mg daily for a limited time did not find any sides or toxicity
Avatar m tn The FDA-approved drug ezetimibe (sold under the trade-name Zetia) is readily available and perfectly targeted to the receptor, Sainz said, so the researchers had an ideal method for testing NPC1L1's involvement in HCV infection. The researchers showed that ezetimibe inhibited HCV infection in cell culture and in mice transplanted with human liver cells. And, unlike any currently available drugs, ezetimibe was able to inhibit infection by all six types of HCV.
Avatar n tn You could consider going for a higher dose of Lipitor, another way to go is to consider taking a drug that limits cholesterol absorption such as Ezetimibe. There is a combination drug Simvastatin and ezetimibe that may be better in controlling cholesterol. Discuss these drugs with your doctor. Best of luck to you. Stay positive.
Avatar m tn A recent paper studied the effect of most FDA approved drugs on the inhibition of NTCP, the now known entry receptor for HBV. Ezetimibe was found to have a 50%inhibition conc of 25micromolar, while irbesartan, a commonly used angiotensin inhibitor to reduce blood pressure, was found to inhibit at 11.9 micromolar. Both compounds have similar MW, but irbesartan is given at up to 300mg per day, while exetimibe is dosed at 10mg.
Avatar m tn no study for its activity on hbv, we do know it has activity but the trial has never started simvastatin lowers hcc 50% and prevents fibrosis/cirrhosis so it is indicated on all hbver, this has thousands of pateints studied for decades to find this data on hcc you better use simvastatin instead other statins, also ezetimibe has in vitro effect on hbv so these are the best choices on hbvers
976897 tn?1379167602 or do they simply take it for granted that you must have this problem if your cholesterol is over a certain value? From 2007 until 6 months ago, I just took atorvastatin 40mg and ezetimibe 10mg and did nothing with my diet to really speak of. Those meds knocked it down to acceptable levels without me doing anything. I then read about sugar consumption playing a huge role in atherosclerosis, and my Doctor even now believes it's probably a mixture of both fats and sugars.
Avatar f tn hi i have just seen your recent post.and i wish i had some answers for you..im so sorry i havent an i can see your frustrated but persevere and keep posting..i just wanted to say hi and let you know people are listening but they maybe just dont have an answer for you..im sure somebody who can relate will come across your post and offer some help or support..
Avatar m tn There was an in vitro study on ezetimibe inhibiting HBV DNA production. The ed50 was fairly low and in a similar range as lamuvidine. So it looked very interesting. But in an in vitro study you have a constant exposure to the drug, which is impossible to achieve in vivo. And the cells used are not the same as regular hepatocytes in human liver, with many differences in gene expression and cellular physiology.
1006041 tn?1250396768 I was given an additional medicine which dramatically decreases the absorbtion of fats through the digestive tract. This is called Ezetimibe and just 10mg reduced my cholesterol a great deal. Maybe your GP could look to attacking your problem from this angle?
Tbd About two years ago my doctor added ezetimibe to my regimen. It has been lowering my bad cholesterol how ever the first of this month I missed taking them for about a week and for the first time in years I felt less fatigued. I do have Fibromyalgia which is usually the cause of my fatigue, but this is a different type of fatigue. I have not restarted either of the cholesterol meds back because I have felt so much better. I know I need to talk to my doctor about it.
Avatar n tn I had very high cholesterol, due to familial hypercholesterolemia, and living on just salad for weeks did nothing for the levels. Statins have worked wonders in bringing the levels down but I also take Ezetimibe which slows absorption of fats through the gut lining. Now I can basically eat what I want and my cholesterol levels are always within the range required. Cholesterol in the blood is not the cause of disease, it's like a side effect from the initial problem.
529224 tn?1400648219 Statins reduced the cholesterol significantly and with the added medication of Ezetimibe, which slows fat absorption through the gut wall, my cholesterol is way below average now. I've been on these medications since the start of 2007 with no side effects which blood tests have continually confirmed. Familial hypercholesterolemia affects 1 in 500 people in many countries, so it isn't that uncommon.
Avatar f tn Hi Everyone. I thought that I'd start a thread about something nice. Can you think of a time when someone (maybe a stranger, maybe not) helped you when you were in pain? For example, for me, sometimes people at the food store offer to help me take the food to my car. The little things mean a lot to me! Does anyone else have any other little things that have touched them? Also, on a side note--and I don't know where to put this...