I was suicidal, had been for 3 months, stopped eating, just anxiety and
fear 24/7 all that time. Effexor
stopped that stuff, took 6 weeks for me but I'm told I was in extreme condition. For me not to eat and not even think of it is certainly a big sign.
It's by far the most effective med for both D and anxiety in my experience. Many worry about coming off but I've been on it now for the third time. First time off, bad side effects, second nothing at all, third, still on it!