In clinical trials of all indications, 31,268 patients were treated with
duloxetine. Of these, 29.5% (9222) took
duloxetine for at least 6 months, and 13.8% (4317) for at least one year.
Cardiac Disorders — Frequent: palpitations; Infrequent: myocardial infarction and tachycardia.
Ear and Labyrinth Disorders — Frequent: vertigo; Infrequent: ear pain and tinnitus.
Endocrine Disorders — Infrequent: hypothyroidism.