100 percent synthetic, causes
it to stay
in the body much longer and not
have the kick in effect, also contains an snri antidepressant that irradic use will cause funky brain zaps, or seizure. Dozens on this website can share experience of trams/ultram, the longer it's used the greater its negative effects. "No" it does not contain a natural bi-product of the opium plant tho some of it bonds to the same receptors.