To help yourself, for both conditions, you should stop drinking and smoking, change your diet
(a must for diabetes
) and exercise regularly. Your wife should get vaccinated for Hepatitis B, if she has no HBsAb. This is a precaution and peace of mind. As for depression, we all get it sometimes, ask your doctor for Prozac, it should help and you can come off it later.
There will be a cure for both conditions in the future.