(29) observed anxiety, depression, hysteria and other somatic complaints, which improved with thyroxine treatment
. Recently Pop et al. (30) found depression
to be significantly related to increased TPOAb levels, but not to subclinical or overt hyper- or hypothyroidism. Nevertheless, the high Odds Ratios (2.9 to 7.9) found by Pop et al. (30) in all these thyroid disorders, even if not statistically significant, are very suggestive.