Certain medications, like those used to treat acne and allergies to
cosmetics and skin-care products, can also contribute to dry and irritated
lips.
Other possibilities are Crohn’s disease (Granulomatous cheilitis, a lumpy swelling of the lips, can be a symptom) and sjogren’s syndrome(an autoimmune disorder in which immune cells attack and destroy the exocrine glands that produce tears and saliva).
Please consult a dermatologist and discuss these possibilities.