Typically, the first dose of a T3 medication, such as Cytomel
or Liothyronine is taken with one's Levothyroxine
in the morning and the second dose around noon/early afternoon; however, there's nothing carved in stone, so you can experiment with the timing and do what works best for you. T3 does not have to be taken on an empty stomach, like Levothyroxine does so there's more leeway in the timing. It can be taken with lunch, just before or just after.