The most important thing to watch with
Copaxone is the
lipoatrophy. Proper rotation of the injection sites will help prevent that, but like many of you, I found that certain sites were difficult or impossible to inject regularly. And if I had an IPIR, I would stop using that area, so eventually the only safe spots were my hips, my thighs, and my stomach. As a result I ended up with quite a bit of lipoatrophy. I've had about six IPIRs.