Copaxone glatiramer acetate

Common Questions and Answers about Copaxone glatiramer acetate

copaxone

Avatar n tn COPAXONE®(glatiramer acetate injection) copaxone (glatiramer acetate) injection [Aventis Pharmaceuticals Inc.] DESCRIPTION ... Patients should be instructed on the safe disposal of full containers ... dailymed.nlm.nih.gov/dailymed/archives/fdaDrugInfo.cfm?
382218 tn?1341181487 New data presented provided evidence that long-term treatment with COPAXONE® (glatiramer acetate injection) may offer sustained protection from neuronal/axonal injury. This protective effect was reflected biologically by a significant increase in N-acetylaspartate (NAA), a specific marker of neuronal mitochondrial function, in treated versus non-treated relapsing-remitting multiple sclerosis (RRMS) patients.
1831849 tn?1383228392 Last time my injection training nurse was over, she mentioned this trial to me. I feel very ambivalent about it, since I would LOVE to inject less often, but I think going off my daily schedule might lead me to forget to inject once in a while... I'm obsessed with compliance.
378497 tn?1232143585 Treatment with glatiramer acetate or the interferon may limit the number of new black holes that became permanent; i.e., reduce progression of brain atrophy, and the interferon seemed to be slightly better at it. There is no control (i.e., untreated) group for comparison of how well the ************** worked vs. no treatment at all.
1713150 tn?1314467342 htm Copaxone is not an interferon - it is a glatiramer acetate - and it also works to get our immune system to work for us and not against us. My neuro likens copaxone to taking the bad cells down to the corner bar, getting them drunk and singing karaoke with them so they forget to do all the bad stuff they had planned. The experts aren't quite sure why copaxone works, but it does. It is made up of amino acids, all of which occur naturally in our body.
Avatar f tn Copaxone is not an immunosuppressant. It's technical name is Glatiramer Acetate, and it is an "immunomodulator". It functions in a way that is not suppression of the immune system. Think of it as more of a decoy. It shifts T cells from Th1 to Th2. In other words, it's a little more sophisticated than just tamping down the immune response. If you are in a severe current flare up, any disease-modifying treatments you begin now will not effect it.
572651 tn?1530999357 Full story Glatiramer-IFN Combo in MS a Toss-Up NEW ORLEANS -- Radiologic findings from a closely watched trial of glatiramer acetate (Copaxone) and interferon-beta-1a (Avonex) combination therapy in multiple sclerosis were mixed, a researcher said here.
198419 tn?1360242356 Keeping up on topic wants (studies)...Oral versus injection is down right exciting! http://www.mscare.org/cmsc/News/CMSC-INForMS-Biogen-Idec-Announces-Positive-Top-Line-Results-from-2nd-PIII-Trial-of-Oral-BG-12. "BG-12 met the CONFIRM study's primary endpoint by significantly reducing annualized relapse rate (ARR) by 44 percent for BID (p< 0.0001) and by 51 percent for TID (p< 0.0001) versus placebo at two years.
Avatar f tn paste from one our Forum leaders, Lulu Copaxone is not an interferon - it is a glatiramer acetate - and it also works to get our immune system to work for us and not against us. My neuro likens copaxone to taking the bad cells down to the corner bar, getting them drunk and singing karaoke with them so they forget to do all the bad stuff they had planned. The experts aren't quite sure why copaxone works, but it does. It is made up of amino acids, all of which occur naturally in our body.
Avatar f tn Okay, first of all, both of these drugs are interferons. That means that it modulates the immune system response to reduce the number of relapses. Both drugs are sub-cutaneous injectables, which means an injection every other day with a very small needle. (This may sound terrible, but it's not so bad. The injection is painless.) I've recently become disenchanted with interferons in general, especially Betaseron.
382218 tn?1341181487 The ongoing US Glatiramer Acetate (GA) Trial is the longest evaluation of continuous immunomodulatory therapy in relapsing–remitting multiple sclerosis (RRMS). The objective of this study was to evaluate up to 15 years of GA as a sole disease-modifying therapy. Two hundred and thirty-two patients received at least one GA dose since study initiation in 1991 (mITT cohort), and 100 (43%, Ongoing cohort) continued as of February 2008.
Avatar f tn I looked at all 4 of the CRABs and their prescribing information. The interferon betas function as an anti-inflammatory and are thought to improve the blood brain barrier. This makes some kind of sense since interferons are a subclass of cytokines (a molecule that provides external signals to cells.) One of the cells cytokines communicate with immune cells. Because cytokines have some control over immune responses, they are classed as immunomodulators. [Wikipedia contributors.
382218 tn?1341181487 These include disease-modifying therapies such as beta-interferons, glatiramer acetate, and natalizumab. Disease-modifying therapies requiring frequent, self-administered injections can be particularly troublesome for some patients, as they may result in localized skin reactions at the injection site. A variety of injection-site reactions (ISRs) have been reported, including pain and erythema, lipoatrophy, abscesses and infections, necrosis, rash, swelling, and lumps.
Avatar m tn Advantage Safe - antihistamines are established drugs with less severe side effects than current MS treatments e.g., interferon-beta, glatiramer acetate, high-dose IV immunoglobulins, monoclonal antibodies against a-4 integrin and steroids) Convenient - oral administration is easier for patients costs to produce and store these compounds are lower than existing treatments" Cost= $5.00 per month I also found the following which should be of interest here: http://www.
Avatar m tn The most important thing to put the flare into a silent mode, and recover! My sister will start her MS treatment. In first line she have chosen copaxone (glatiramer-acetate), she dont want to experience flu like sympthoms so she rejected betaferon, and avonex. In second line (if the first line treatment ineffective) she may chose tysabri (natalizumab) or gilenya (fingolimod). Fortunately RRMS'ers nowadays have a lot of effective treatments to fight against this desease.
Avatar n tn Also a study published in the August issue of Neurology showed that Copaxone® (glatiramer acetate for injection) reduced by 50 percent the percentage of permanent "black holes" that developed in patients with relapsing-remitting multiple sclerosis. Black holes are lesions MS can cause in the brain, and these lesions, if permanent, represent areas where the most severe and irreversible brain tissue damage has occurred.
Avatar n tn There are generic versions of Copaxone (glatiramer acetate) coming out from Momenta Pharmaceuticals and Mylan. The FDA rejected a petition from Teva in March which should clear the way for a generic to be made available. That's about the only one I know of.
Avatar n tn 39–45 These studies suggested that early initiation of disease modification after a first clinical episode including treatment with interferons (IFN beta-1a and IFN beta 1-b) or glatiramer acetate would be beneficial in lowering the risk of conversion to MS as well as decreasing development of new T2 lesions on MRI.
Avatar n tn I have a very mild form of MS and take a daily injectable medication called glatiramer acetate...not sure if that could be the cause of the problem? Any suggestions would be appreciated.
Avatar f tn My neuro describes the difference between the interferons (betaseron, rebif and avonex) and glatiramer acetate( copaxone) as similar to a pepsi/coke challenge. they are all the same, it just depends on personal preference as to which one you like better. Is your doctor offering you copaxoneThe side effects we know from copaxone, after 18 years of use, is the lipotrophy. Period. There are no liver problems. No difficulty with drug induced depression. You do have to inject daily.