copaxone and mitoxantrone

Anyway, I stopped Rebif and started on Copaxone last June, and in July, saw a neuro at the Partners MS Center in Boston at Brigham & Women's Hosp, for a second opinion on the mitoxantrone, if things didn't stabilize for me. He told me very bluntly "We hate that drug here." He felt it should be a last resort due to its toxicity to the heart. His recommendation if Copaxone didn't help me, was to try Tysabri first.

This article was written by the neuro I saw in Boston a couple of years ago to get a second opinion on mitoxantrone. At the time my newly dx'ed RRMS was very active/aggressive (serious relapses every few months) and my regular neuro suggested I might need to consider this more aggressive treatment. I was worried about all I had read about this drug; sought Dr. Stankiewicz's opinion, and he said flat out "We [Partners MS Center in Boston] hate that drug.

My son is currently on mitoxantrone treatment. He has had approx. 6 rounds of it so far. They also give it to him in conjunction with prednisone. HE goes every 3 months to an infusion center to have it administered. It is done through IV's and so far other than a little nausea, which they give him meds for he has done pretty well on it. HE hasn't had an exasperbation in 16 months. He normally has one about every 8 months, so we thinks this is really good.

thank you both for your comments, DV no Gilenya has not been mentioned to me, so far they just have talked Copaxone, Avonex , and the Mitoxantrone ... ( like chemo ) .... I am going to speak with the MS Nurse again on Monday, on the other alternatives that we have talked about.

m going thru my second round of IV steroids. I am supposed to start Copaxone tomorrow and am nervous about the side effects and if I should start it while going thru Steroid treatments. Any advice would be much appreciated!

Objective response rates were 10 to 20 percent, and median survival did not exceed 12 months. However, newer regimens, based upon docetaxel and mitoxantrone, have resulted in objective responses and clinical benefit. In the 1990s, two randomized trials showed that mitoxantrone plus a corticosteroid improved palliative endpoints, but not survival, compared to a corticosteroid alone.

Other drugs used are cyclophosphamide and Mitoxantrone. Then there is supportive drug therapy for symptoms. Please talk to your doctor regarding all this. Take care! The medical advice given should not be considered a substitute for medical care provided by a doctor who can examine you. The advice may not be completely correct for you as the doctor cannot examine you and does not know your complete medical history.

Hi and welcome, As far as i'm aware IV solumedrol and Copaxone are often being done together, i've never personally heard of specific interaction problems, usually the choices you get is to stay on Copaxone and do the IV Steroid (with or without oral taper) or stay on Copaxone and skip the Steroids if it's not a major relapse.

Hi, I to am on Copaxone and have been for 4 months as well, and I can't say that I have gained weight... sorry, but I too watch calories all the time so have not noticed to much difference. Hope you can get to the bottom of it ...

my husband is on copaxone and his back hurts severely. also his hands hurt and he is having asthma type reactions. also he is having dizziness and frequency in urinating. eye problems as well. please tell me if anyone else is having these disturbing things.

(Pill and other forms) I too, was loosing CLUMPS of hair and it has now stopped. I have been on Copaxone for 8 months now and had the same experiance at the 4-5 month mark. Best wishes!!!

I went off the copaxone when I went into the hospital and have been off of it for almost 2 months now. How long does the copaxone stay in your system after you stop taking it? Anyone have low platelet counts?

I am a MS training nurse, I train on all of the injectable and most of the IV drugs. Rebif, Avonex, Copaxone, Betaserone and Extavia are all first line of defense drugs. Rebif and Extavia and Avonex are the same drug. Avonex is the smallest dose but the biggest needle. Extavia is a larger dose than Rebif, simply because it is every other day, as Rebif is 3x a week. Copaxone is the most compatable with your natural body and has the least side effects, but is a daily injection .

I'll start with the bad - I started back on Copaxone and it's been H*LL! When I first used Copaxone it was a breeze, not issues whatsoever. This time the pain from the injections is extreme and I have fist size bruises all over my thighs and tummy! I hate it! The good news is I went to see the Optic Neurologist this week and she is wonderful. I've never met a Doctor who takes such care to make sure I understand everything that is happening to me.

Ive been on Copaxone for 5 months now and 2 months in had a mild flair of symptoms then it went away. It was trigeminal neuralgia for 3 days then it went away for 3 days then I was hit with extreme fatigue for 3 days where I had to sleep. I developed jumpy jerky arms and legs but medication helped this.

I went off the copaxone when I went into the hospital and have been off of it for almost 2 months now. How long does the copaxone stay in your system after you stop taking it? Has anyone had problems with low platelet count with MS or medicines?

In Feb 08 I began taking Copaxone for MS. Shortly after I began using Copaxone, the right side of my tongue went numb. I initially stopped taking the Copaxone to see if it would resolve itself. It didn't and I continued with the Copaxone. The right side of my tongue is still numb, the numbness on the right side of my mouth has resolved mostly but now I have the most horribly dry mouth. I have tried everything--even so much as sucking on a mouth full of vinegar.

I'm curious how long it took for those on Copaxone for the welts and redness to lessen. I've been on Copaxone since June and it seems they are getting worse. The first two or so weeks I did not have much of a problem. Then I started to get large red patches/lumps on my arms. They can run the length of my back arm where I give my shots. Weeks later they started to get large on my legs (the size on my entire hand at times). Eventually they started to get large on my hips and abdomen.

I have MS treated with Copaxone. It has been suggested that I try a product called PROTEIN 7 SYNTHESIS...

Copaxone and mitoxantrone

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