copaxone and liver

Restarted Rebif and only Rebif, stayed off the other meds, alcohol, etc, and liver enzymes shot up again after only a weeek or two. So I stopped and immediately started Copaxone. This was nearly 5 years ago. I've had no side effects other than the inital site reactions and one minor IPIR episode. On Copaxone my attacks went from 4 in a little over a year to 1 every 2-3 years on average.

The effectiveness of both is very similar. It comes down to whether one can tolerate their respective side effects, and how they would fit into your lifestyle ie 3x week injection vs daily. I had a brief trial run on Rebif but had to discontinue as it elevated my liver enzymes too much. I never made it up to the full dose which may explain why I never experienced flu like symptoms. The shot itself was painless with no site reaction. I switched to Copaxone and was on it for six years.

I was on Copaxone for 4 years and it was not effective . During that time I had many major flare ups and suffered per permanent mobility damage. 2 years ago I switched to Gilenya plus a steroid infusion routine and I have been doing great! No flare ups at all. I have felt well the entire time I was on Gilenya. Unfortunately my latest blood test just came back. The results showed my liver enzymes rose off the charts. My neuro had me stop talking the Gilenya immediately.

I was in this bottom 3% and after two attempts, ruling out any other possible culprits (normal baseline, then no alcohol, supplements or any other medication for the trial run on Rebif), I went off Rebif at the advice of my neuro, who treated this all very seriously, and went on Copaxone June of 2008. My liver enzymes promptly returned to normal, and I am tolerating this med well ; it has no neg effect on the liver.

I have been on both Rebif and Copaxone. I was on Rebif for about 5 years, and I have been on Copaxone for two. I didn't have any problems with the Rebif except for the high liver functions. That is why I am on Copaxone. I think there is no difference in the injection pain. They both were very minimal. My worst pain was in my arms for some reason. The daily injections aren't bad, especially since you don't get sick.

He recommends Avonex because my sister is on that and she is doing great. I am leaning toward Copaxone because it is the one with the least side affects. I am not too fond of giving myself a shot everyday but I don't want to have to worry about liver problems and flu like symptoms either. My sister has been on Avonex for the past 8 years and she is doing remarkable. I love the fact that she is doing well, but I am not fond of the weekly intramuscular shot, I know waaaa what a baby lol.

my husband is on copaxone and his back hurts severely. also his hands hurt and he is having asthma type reactions. also he is having dizziness and frequency in urinating. eye problems as well. please tell me if anyone else is having these disturbing things.

ll officially diagnose me w/ MS. He sent me home with literature on Avonex and Copaxone to read and decide which med I want to start. I am suppose to call him the middle of next week for my lab results and let him know which med I want to start. I'm thinking of starting Copaxone cuz little to no side effects and its not metabolized through your liver. But, does it slow the progression of the disease like Avonex?

1) Has anyone taken a break from their medication for that long (and if so, any consequences) and 2) Has anyone switched from Avonex to Copaxone, and if so, how did you do? I still after all these years lose a day on the weekend due to the side effects of the Avonex and am hoping that will not be the result with Copaxone.

blah blah of the liver. So now, I have to go for a 3 phase CT of my liver on Wednesday (radiologist recommended). Frankly, I'm scared spitless. Any encouragement you can give me Quix? I stopped the copaxone because the injection site reactions were awful. My neuro said he figured that was going to happen when I started having reactions, but at least I got about a year on it. I also found out my vitamin D is very low at 12, so I'm probably going to be going on prescription D3.

t flu-like side effects and the risk of liver damage is less (my dad died of liver failure after taking immunosuppressants) The only thing putting me off is the injections themselves as I've got very bad hyperhidrosis in my hands and am scared the needle will slip or something. Would Tysabari be a better choice for me in that case? Help please!

m going thru my second round of IV steroids. I am supposed to start Copaxone tomorrow and am nervous about the side effects and if I should start it while going thru Steroid treatments. Any advice would be much appreciated!

t sit here and lie to you, injection site reactions ARE a part of using Copaxone. They just get less huge and less stinging and painful, the more you use it. I have NO side effects from the Copaxone at all, except for the injection site. No flu like side effects like with the Interferons and no pre-medicating with Tylemol or Advil, like I did when I was using the Interferons. I took Avonex for three years and it was a GREAT drug at slowing down the MS.

So for all these reasons I think I should kiss Rebif goodbye now, and give Copaxone a try, and hope I don’t have the problems that Ess and Gollie have experienced. It is frustrating that I live so far from my MS clinic. I am considering emailing my neuro tomorrow stating my concerns and requesting he consider Copaxone now rather than waiting it out with Rebif. My question to you is…..if you were in my shoes, what do you think you would do? I would be grateful for your insight on this.

Hi and welcome, As far as i'm aware IV solumedrol and Copaxone are often being done together, i've never personally heard of specific interaction problems, usually the choices you get is to stay on Copaxone and do the IV Steroid (with or without oral taper) or stay on Copaxone and skip the Steroids if it's not a major relapse.

hi Marizzy, and welcome to the forum. I can say that since this is your first post! I'm glad you have decided to join in the conversation. I am also a heart patient - I had a heart attack last year at the age of 53. I am fine but do remain aware of all things cardio. Have you called the Rebif hotline and talked to them about side effects? I am on copaxone and very know little about the other DMD's and their side effects, but I will look and see if I can find some answers.

Hi, I to am on Copaxone and have been for 4 months as well, and I can't say that I have gained weight... sorry, but I too watch calories all the time so have not noticed to much difference. Hope you can get to the bottom of it ...

Copaxone and liver

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