I am sure if you are not already on antidepressants, a good psychiatrist will get you started on them a few weeks before you start Hep C treatment.
It is doable with the right care and treatment
I also have a history of clinical depression
and have been on ADs twice. I am currently on Hep C treatment with triple med treatment and I am currently taking an AD. I have had no problem with depression, mood swings, anxiety, anything mental/emotional, since starting triple med treatment in Sept.