Some women find that trying a different brand can make a world of difference such as switching from
Vivelle-Dot or Minivelle (3 day patch) to
Climara (7 day patch). They have different adhesives that can affect uptake of the estrogen. The Vivelle-Dot did not work well for me and I didn't know any better to try Climara.
If the patch doesn't work out, there are pills, gels, and vaginal rings you can try. Hope you find something that helps soon! I know how desperate it can feel!