During this time you may be unsure whether you’re experiencing symptoms of discontinuation or lingering
side effects from the drug remaining in your system. To determine how
long Chantix stays in your system, it is necessary to know its elimination half-life.
The elimination half-life of Chantix is approximately 24 hours, meaning it takes around 1 full day after your last dose to eliminate 50% of the drug from systemic circulation.