According to Uptodate, the medications that cause this condition include colchicine, nondepolarizing muscle relaxers with high doses of corticosteroids, antimalarials, niacin, penicillamine, fibrates, zidovudine and statins. Drugs that
can cause elevated liver enzymes include cocaine and alcohol, particularly when they are abused.
Testing patients for elevated muscle enzymes helps doctors determine the cause and can help to evaluate muscle pain, weakness and inflammation.