Hello,
Wellbutrin can cause skin redness, itching and increased sweating but it is not known to cause skin wrinkling. The most important
treatment of skin wrinkling is avoiding the sun and using sunscreens with minimum spf of 30 atleast half an hour before going out in the sun. Other treatment methods include prescription acid creams or peels, stronger retinoids such as Retin A, Botox( botulinum toxin) ,non invasive or carbon dioxide laser and a surgical facelift.