Breast cancer genetic testing

Common Questions and Answers about Breast cancer genetic testing


Avatar f tn Hi Everyone- I am new to this site and am happy to see the support and wonderful people who contribute here. I have a question about genetic testing for breast cancer. I was diagnosed with small cell ovarian cancer in 1995 and things have went extremely well since then. Recently my cousin (on my mother's side) was diagnosed with breast cancer (age 38). My doctors are now suggesting that I get genetically tested for breast cancer.
Avatar f tn The one sister with cancer wants her ovaries removed-but the surgeon won't remove them without genetic testing. This does not make sense because cancer is cancer. Why let the ugly disease spread? So, the other three of us without cancer get to sit and wait in limbo until we get a positive mamogram. Is this right-or should we be seeking other surgeons, or will the outcome be the same. I am not asking for surgery-but I also do not want to die of cancer.
Avatar n tn Women with node-negative, estrogen-receptor-positive invasive breast cancer, and post-menopausal women with node-positive, hormone-receptor-positive invasive breast cancer are eligible." All the best, and God Bless!
Avatar n tn But either way it means that you already have a very high increased risk for breast cancer and should seek advice from a genetic counselor who can explain your risks to you and explain BRCA mutations too. The best advice will come from a BRCA savvy counselor whether or not you have the mutation. You will also find a bunch of information at www.facingourrisk.
Avatar n tn MY mom passed at 71 yrs old with Breast Cancer that had spread to the bone. My sister was diagnoised with it at age 59 had breast removed. Four years later she got it in her other breast. I am 57 and scared. Is it wise I should have test done? How accurate is the test? Help..
Avatar f tn My paternal family history is riddled with cancer. One aunt and one uncle died of pancreatic cancer; one uncle has colon cancer in remission, my father has prostate cancer in remission, one aunt being told tomorrow what her blood work with red flags shows and another uncle who has not gone back to get his results. I discussed having genetic testing done with my NPA and she did not recommend it. What should I do? I'm very concerned. I have had a tubal ligation and a uterine ablation.
531852 tn?1226030011 If you are tested positive, you'd be at very high risk for breast cancer, for example BRCA2 positive women can be as high as 84% for breast and 40% for ovca. Of course, noone really knows the % for sure. Two genes have been identified, BRCA1 and BRCA2. If you are positive, at a minimum you should enroll in a high risk screening program that includes doc breast exams and alternating MRIs and digital mammograms every 6 months. Just being monitored by a doctor is not enough.
Avatar f tn But this risk reduction is at most 50% and may not reduce risk in someone who has a genetic risk. Checking ultrasounds will not protect you. Ovarian cancer spreads by shedding and spreading seeds of small malignant cells around the abdominal cavity before the ovary is even enlarged. If you have completed your family and if based on the results of a good genetic evaluation, you are considered high risk for ovarian cancer, surgical intervention is indicated.
684030 tn?1415615923 and, given my own history of developing abnormal yet non-cancerous growths in my breast, the radiologist’s recommendation was for me to undergo genetic testing. On the other hand, my lifelong family physician questions the value of this approach, “… knowing that [I] will not be having children.” I’m somewhat inclined to agree with my doctor... and forgo testing. However, my mother (whose two sisters died of Breast Cancer) is pushing for it...
Avatar f tn My daughter (39) has been diagnosed with breast cancer and had a mastectomy with all lymph nodes removed on her left side. She is classed as grade 3, Stage 2. Her chemo will start in ten days and radiation to follow. She also had the genetic testing done a few weeks back. The results were given to us Thursday. Does that change her grade and or stage? Will her chemo treatment change? I know she will be having another mastectomy and ovaries removed later.
Avatar m tn I'm working for a genetic and paternity testing company in South Africa, GENEDiagnostics. We test for a variety of diseases including heart diseases, strokes, prostate- and breast cancer, hereditary haemochromatosis, lactose intolerance, cystic fibrosis etc. I want to find out what people know about genetic testing and what their biggest needs and concerns are. Hopefully, MedHelp will help me find out more.
Avatar f tn I realize that this is kind of off the subject but, I would like your opinion on genetic testing. I am concerned that it will flag me and my family for health ins. and life ins. There is a question of whether my mother has men or not. There are 9 kids in our family, plus our children. I so far have had a single parathyroid adenoma and small goiter. I do have multiple medical problems that being treated, which include kidney stones. My labs are good except my K+, which is low.
Avatar f tn about 10% of all women who develop ovarian cancer have a family history by definition familial ovarian cancer is having two or more first degree family members with ovarian cancer or having the genetic testing that nyc describes for those with this syndrome, they have up to an 40% risk of developing ovarian cancer here is a good site for more info http://www.cancer.
Avatar m tn I'm sending you the address of the Mayo Clinic web page on genetic testing for breast cancer. Not all women need this kind of screening procedure. The web page lists down criteria if this test is appropriate for you. You can go to: http://www.mayoclinic.
885049 tn?1277421930 1. the genetic variations associated with hereditary breast and ovarian cancer 2. the way that heredity contributes to the condition, including the risk of recurrence (occurrence) of cancer 3. ways to cope and adjust to the risk 4. an appropriate course of action in view of cancer risk, family goals and personal views Health professionals who specialize in cancer genetics can be found at the National Cancer Institute website.
Avatar n tn Hi. Risk factors for the development of breast cancer include age, reproductive history, family and personal history of breast cancer, and exposures to specific carcinogens. You have a high risk of developing breast cancer based on the strong family history. The risk of developing breast cancer by age 70 is about 45% to 87% for those with BRCA1 mutations while it is about 26% to 84% for those with BRCA2 mutations. Since you are at risk, you may undergo genetic testing.
184674 tn?1360864093 After unintentionally coming across a health article about cancer and genetics, I found that there is a potentially higher risk of women getting ovarian cancer if colorectal cancer and breast cancer are diagnosed among family members. Well, as far as I know, ovarian cancer has not touched my family, but breast cancer has on both sides of my family and colorectal cancer in my mom--plus my mom just informed me today that she's had a history of chronic ovarian cysts before menopause.
1372123 tn?1280753511 Hello, im wondering how high are my risks of getting Breast Cancer. My mom had a lump that was found in her breast out and checked but then it was benied. Almost a year later, she was diagnosed with Leukimia and died 6 months later. She had an aunt who died of Breast Cancer and I recently learn that my dad has sisters with Breast Cancer as wel. So many secrets in my family but glad im finding out all I can. There are so many conditions in y family both on my dad and mothers side.
Avatar n tn So do you have breast cancer or are you preying on us that do? I should have picked up on the name but dummy me. If you don't have cancer you could have told us you were a reporter and ask our opionn but from your post it seems you a in the same boat we are. I don't play mind games. Until you explain further I am very frustrated with you.
Avatar m tn previous history of breast cancer, a mass with atypical hyperplasia on biopsy, strong family history or genetic predisposition (e.g. BRCA 1 and 2 genes), prior radiotherapy to the chest, or a five-year risk of invasive breast cancer of at least 1.7% in women 35 years or older, using the modified Gail model for calculating risk (see There is no blood test available at present which can be reliably used for breast cancer screening.
Avatar n tn My paternal grandmother got breast cancer in her mid 30's. I for some reason take after her, same weight, stature and so on. My maternal aunts, cousins and my mother all have to have lumps removed from there breasts every other years since they were in there late 30's. My maternal aunt just got diagnosed at age 60 for breast cancer. I talked to my dr and she won't even hear about doing a mamagram until 35. She won't give me the Braca 1 and Braca 2 test.
Avatar n tn Mother, father, and sister had breast cancer. I just received a call to have my left breast xrayed again because they found asymmetrical density on the left side that wasn't there last year. I'm really worried. Dr. can't see for two days.
Avatar f tn Met with breast surgeon who ordered BRCA 1 and 2 genetic testing--Negative results. She recommended bilateral simple mastectomies (prophylactic on the left?) and I have this scheduled for 8/9/11. I am wondering if this is overkill at my age? She will do bilateral sentinel node biopsies, also. 21 years ago, 13 nodes were removed on the right and all were negative.
Avatar n tn The rate increase is less then 10 percent when a first line family member, mother, sister, have had breast, colon and/or ovarian cancer. There is genetic testing BRCA 1 and BRCA 2 which let's you know if you are a "carrier". If these tests come back positive then your increased risk is 40 percent. The important thing to remember is that most OvCa are sporatic, and it is a very rare disease.
Avatar n tn The familial risk of breast cancer is most closely associated with first degree relatives (mother, sister, daughter). The genetic form of breast cancer (BRCA1 and BRCA2) that we currently know is relatively uncommon. There is testing for these genes. It is usually offered when there are more than 2 first degree relatives with breast cancer whose situations meet criteria suggesting that the cancer may be inherited. Usually, the person WITH the cancer is tested first.
886824 tn?1253740254 Women who have a mutation in either of these genes, have an estimated 60%-80% lifetime risk to develop breast cancer and an estimated 20%-40% lifetime risk to develop ovarian cancer depending on if there is a family history of ovarian cancer, breast and ovarian cancer, or breast cancer alone. Males with a mutation in either of the BRCA1 or BRCA2 genes have a lower breast cancer risk, but it is still higher than the general population.
Avatar n tn You will get cancer. Already 3 cousins 1 aunt and 2 2nd cousins have recently had breast cancer and the procedures to save them from it. Don't forget my mother who as the rest of the family had breast cancer at 33 beat it then about 20 years later had ovarian and now its gone to brain. Something else we don't know or at least i've never been told is if the Brain cancer is related to the ovarian as in cells broke off and traveled or if it's own type of cancer.
Avatar f tn Genetic testing is very simple. It is just a blood test that shows if you have the gene for breast cancer. Just because you have the gene does not mean that you will definetly get breast cancer. My mother has had BC twice at an early age. I recently found out that I have 3 intramammary lymph nodes that they are watching. The surgeon discussed with me about having genetic counseling. Here is his thoughts on it. If the test comes back positive for the gene what would you want done?