Yes, there is a difference. The glucose
meter measures blood
sugar at that exact moment. The A1C, on the other hand, gives an average of blood sugars for about 2-3 months period. The A1C therefore, gives a lot more significant information but it can also be misleading. For example of someone has a lot of highs, but also a lot of lows, it might average out and look like the person is maintaining a good blood glucose level when they are, in fact, swinging wildly.